Drug repurposing strategies for non-cancer to cancer therapeutics
S Singhal, P Maheshwari… - Anti-Cancer Agents …, 2022 - ingentaconnect.com
Global efforts invested in the prevention and treatment of cancer need to be repositioned to
develop safe, effective, and economic anticancer therapeutics by adopting rational …
develop safe, effective, and economic anticancer therapeutics by adopting rational …
[HTML][HTML] Drug repurposing: re-inventing therapies for cancer without re-entering the development pipeline—a review
S Siddiqui, AJ Deshmukh, P Mudaliar… - Journal of the Egyptian …, 2022 - Springer
While majority of the current treatment approaches for cancer remain expensive and are
associated with several side effects, development of new treatment modalities takes a …
associated with several side effects, development of new treatment modalities takes a …
[HTML][HTML] “Drug Repurposing for Cancer Therapies”
CPR Xavier, A Palmeira - International Journal of Molecular Sciences, 2024 - mdpi.com
Cancer is one of the primary global causes of death, thus addressing cancer therapy
remains a significant challenge, especially in cases where cancers exhibit resistance to …
remains a significant challenge, especially in cases where cancers exhibit resistance to …
Drug repurposing for cancer therapy—an introduction
P Pantziarka, L Meheus, K Rombauts… - Drug repurposing in …, 2020 - Elsevier
Repurposing is a drug development strategy that seeks new medical treatments using
existing licensed drugs rather than from new molecular entities. There has been increasing …
existing licensed drugs rather than from new molecular entities. There has been increasing …
Repurposing of drugs: An attractive pharmacological strategy for cancer therapeutics
A Kirtonia, K Gala, SG Fernandes, G Pandya… - Seminars in cancer …, 2021 - Elsevier
Human malignancies are one of the major health-related issues though out the world and
anticipated to rise in the future. The development of novel drugs/agents requires a huge …
anticipated to rise in the future. The development of novel drugs/agents requires a huge …
Drug repurposing in the development of anticancer agents
S Olgen, LP Kotra - Current medicinal chemistry, 2019 - ingentaconnect.com
Background: Research into repositioning known drugs to treat cancer other than the
originally intended disease continues to grow and develop, encouraged in part, by several …
originally intended disease continues to grow and develop, encouraged in part, by several …
Drug repurposing for cancer therapy, easier said than done
A Gonzalez-Fierro, A Dueñas-González - Seminars in cancer biology, 2021 - Elsevier
Drug repurposing for cancer therapy is currently a hot topic of research. Theoretically, in
contrast to the known hurdles of developing new molecular entities, the approach of …
contrast to the known hurdles of developing new molecular entities, the approach of …
[HTML][HTML] Drug repurposing for cancer therapy
Y Xia, M Sun, H Huang, WL Jin - Signal Transduction and Targeted …, 2024 - nature.com
Cancer, a complex and multifactorial disease, presents a significant challenge to global
health. Despite significant advances in surgical, radiotherapeutic and immunological …
health. Despite significant advances in surgical, radiotherapeutic and immunological …
[HTML][HTML] Repurposing drugs in oncology: next steps
C Verbaanderd, L Meheus, I Huys, P Pantziarka - Trends in cancer, 2017 - cell.com
The repurposing of existing non-cancer drugs is a potential source of new treatment options
for cancer patients with high unmet medical needs. While scientific research is progressing …
for cancer patients with high unmet medical needs. While scientific research is progressing …
[HTML][HTML] Repurposing approved non-oncology drugs for cancer therapy: a comprehensive review of mechanisms, efficacy, and clinical prospects
Cancer poses a significant global health challenge, with predictions of increasing
prevalence in the coming years due to limited prevention, late diagnosis, and inadequate …
prevalence in the coming years due to limited prevention, late diagnosis, and inadequate …