Background & Aims Previous studies demonstrated that autophagy is protective in
hepatocytes and macrophages, but detrimental in hepatic stellate cells in chronic liver …

Autophagy is a critical pathway for the degradation of intracellular components by
lysosomes. Established functions for both macroautophagy and chaperone-mediated …

Liver fibrosis (LF) occurs as a result of persistent liver injury and can be defined as a
pathologic, chronic, wound‐healing process in which functional parenchyma is …

The pathogenesis of liver fibrosis in nonalcoholic fatty liver disease (NAFLD) remains
unclear and the effective treatments have not been explored yet. The activation of hepatic …

Background & Aims Endothelial dysfunction plays an essential role in liver injury, yet the
phenotypic regulation of liver sinusoidal endothelial cells (LSECs) remains unknown …

BACKGROUND & AIMS: Autophagy is a metabolic process that degrades and recycles
intracellular organelles and proteins with many connections to human disease and …

Autophagy is a lysosomal degradative pathway that functions to promote cell survival by
supplying energy in times of stress or by removing damaged organelles and proteins after …

Background & Aims Autophagy plays a crucial role in hepatic homeostasis and its
deregulation has been associated with chronic liver disease. However, the effect of …

Alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD) are the leading
causes of cirrhosis and increase the risk of hepatocellular carcinoma and liver-related death …

Autophagy, or cellular self‐digestion, is a catabolic process that targets cell constituents
including damaged organelles, unfolded proteins, and intracellular pathogens to lysosomes …