[HTML][HTML] Recurrent or primary metastatic cervical cancer: current and future treatments

C Gennigens, G Jerusalem, L Lapaille, M De Cuypere… - ESMO open, 2022 - Elsevier
Despite screening programs for early detection and the approval of human papillomavirus
vaccines, around 6% of women with cervical cancer (CC) are discovered with primary …

Targeted treatment options for the management of metastatic/persistent and recurrent cervical cancer

L Mutlu, J Tymon-Rosario, J Harold… - Expert review of …, 2022 - Taylor & Francis
Introduction Cervical cancer is the overall fourth most common malignancy and the fourth
most common cause of cancer-related deaths worldwide. Despite vaccination and screening …

Management of patients with recurrent/advanced cervical cancer beyond first line platinum regimens: Where do we stand? A literature review

S Boussios, E Seraj, G Zarkavelis, D Petrakis… - Critical reviews in …, 2016 - Elsevier
Background Cervical cancer is the fourth most common cancer affecting women worldwide.
Despite advances in screening and human papillomavirus (HPV) vaccination, a significant …

[HTML][HTML] Cervical cancer: part II the landscape of treatment for persistent, recurrent and metastatic diseases (I)

ST Yang, PH Wang, HH Liu, CW Chang… - Taiwanese Journal of …, 2024 - Elsevier
Abstract The WHO (World Health Organization) conducted an elimination of cervical cancer
program using triple pillar intervention strategy to target 90%-70%-90% of women before the …

Novel therapeutics for recurrent cervical cancer: moving towards personalized therapy

AC Cohen, BM Roane, CA Leath III - Drugs, 2020 - Springer
While screening programs and HPV vaccination have decreased the incidence of cervical
cancer, still over 13,000 cases occur in the USA annually. Early-stage cervical cancer has …

Atezolizumab plus bevacizumab and chemotherapy for metastatic, persistent, or recurrent cervical cancer (BEATcc): a randomised, open-label, phase 3 trial

A Oaknin, L Gladieff, J Martínez-García, G Villacampa… - The Lancet, 2024 - thelancet.com
Background The GOG240 trial established bevacizumab with chemotherapy as standard
first-line therapy for metastatic or recurrent cervical cancer. In the BEATcc trial (ENGOT-Cx10 …

[HTML][HTML] Targeted therapy in cervical cancer

C Vora, S Gupta - ESMO open, 2018 - Elsevier
Cervical cancer continues to be a common cancer in women worldwide, especially in less
developed regions where advanced stage presentations are common. Addition of …

A randomized phase III trial of platinum chemotherapy plus paclitaxel with bevacizumab and atezolizumab versus platinum chemotherapy plus paclitaxel and …

JF Grau, L Farinas-Madrid, A Oaknin - International Journal of …, 2020 - ijgc.bmj.com
Background Patients with metastatic, recurrent, or persistent cervical cancer not amenable to
local control and/or distant metastases have a very poor prognosis, only being candidates …

Developments in the systemic treatment of metastatic cervical cancer

G Mountzios, A Soultati, D Pectasides… - Cancer treatment …, 2013 - Elsevier
Despite the available prevention and early detection strategies, advanced squamous-cell
carcinoma of the uterine cervix remains a major concern for public health. Systemic …

[HTML][HTML] Treatment options in recurrent cervical cancer

A Gadducci, R Tana, S Cosio… - Oncology …, 2010 - spandidos-publications.com
The management of recurrent cervical cancer depends mainly on previous treatment and on
the site and extent of recurrence. Concurrent cisplatin-based chemo-radiation is the …