It is well-established that aberrant WNT expression and signaling is associated with
developmental defects, malignant transformation and carcinogenesis. More recently, WNT …

The host-pathogen interface is a crucial battleground during bacterial infection in which host
defenses are met with an array of bacterial counter-mechanisms whereby the invader aims …

Cell differentiation, proliferation, and death are vital for immune homeostasis. Wnt signaling
plays essential roles in processes across species. The roles of Wnt signaling proteins and …

A fundamental puzzle in immunology is how the immune system launches robust immunity
against pathogens while maintaining a state of tolerance to the body's own tissues and the …

The body of scientific literature linking Wnts and Wnt-associated proteins to human disease
processes continues to grow in parallel with new discoveries from basic science laboratories …

Wnt proteins comprise a large family of highly conserved glycoproteins known for their role
in development, cell fate specification, tissue regeneration, and tissue homeostasis …

Wnt signaling is one of the important pathways to play a major role in various biological
processes, such as embryonic stem-cell development, tissue regeneration, cell …

Wnt ligands interact with the transmembrane cell surface receptors Frizzled and ROR/RYK
to initiate complex signaling cascades that are crucial for cell physiology and the proper …

Wnt proteins are secreted, palmitoylated glycoproteins with multiple functions in cell
proliferation and migration as well as tissue organization. They are best known for their role …

The evolutionarily conserved Wnt signaling pathway plays a central role in development and
adult tissue homeostasis across species. Wnt proteins are secreted, lipid-modified signaling …