Differences between plasma and cerebrospinal fluid glial fibrillary acidic protein levels across the Alzheimer disease continuum
AL Benedet, M Milà-Alomà, A Vrillon, NJ Ashton… - JAMA …, 2021 - jamanetwork.com
Importance Glial fibrillary acidic protein (GFAP) is a marker of reactive astrogliosis that
increases in the cerebrospinal fluid (CSF) and blood of individuals with Alzheimer disease …
increases in the cerebrospinal fluid (CSF) and blood of individuals with Alzheimer disease …
Plasma glial fibrillary acidic protein in the Alzheimer disease continuum: relationship to other biomarkers, differential diagnosis, and prediction of clinical progression
XN Shen, SY Huang, M Cui, QH Zhao, Y Guo… - Clinical …, 2023 - academic.oup.com
Background Plasma glial fibrillary acidic protein (GFAP) has emerged as a promising
biomarker in neurological disorders, but further evidence is required in relation to its …
biomarker in neurological disorders, but further evidence is required in relation to its …
[HTML][HTML] Plasma glial fibrillary acidic protein detects Alzheimer pathology and predicts future conversion to Alzheimer dementia in patients with mild cognitive …
C Cicognola, S Janelidze, J Hertze… - Alzheimer's research & …, 2021 - Springer
Introduction Plasma glial fibrillary acidic protein (GFAP) is a marker of astroglial activation
and astrocytosis. We assessed the ability of plasma GFAP to detect Alzheimer's disease …
and astrocytosis. We assessed the ability of plasma GFAP to detect Alzheimer's disease …
Plasma glial fibrillary acidic protein levels differ along the spectra of amyloid burden and clinical disease stage
Background: Measuring plasma glial fibrillary acidic protein (GFAP) alongside cortical
amyloid-β (Aβ) may shed light on astrocytic changes in aging and Alzheimer's disease (AD) …
amyloid-β (Aβ) may shed light on astrocytic changes in aging and Alzheimer's disease (AD) …
Differences between blood and cerebrospinal fluid glial fibrillary Acidic protein levels: The effect of sample stability
Introduction Recent evidence has shown that the marker of reactive astrogliosis, glial
fibrillary acidic protein (GFAP), has a stronger relationship with cerebral amyloid beta (Aβ) …
fibrillary acidic protein (GFAP), has a stronger relationship with cerebral amyloid beta (Aβ) …
[HTML][HTML] Plasma glial fibrillary acidic protein is elevated in cognitively normal older adults at risk of Alzheimer's disease
P Chatterjee, S Pedrini, E Stoops, K Goozee… - Translational …, 2021 - nature.com
Glial fibrillary acidic protein (GFAP), an astrocytic cytoskeletal protein, can be measured in
blood samples, and has been associated with Alzheimer's disease (AD). However, plasma …
blood samples, and has been associated with Alzheimer's disease (AD). However, plasma …
Glial fibrillary acidic protein in serum is increased in Alzheimer's disease and correlates with cognitive impairment
P Oeckl, S Halbgebauer… - Journal of …, 2019 - content.iospress.com
Reliable blood biomarkers for Alzheimer's disease (AD) are missing. We measured
astroglial GFAP in patients with AD (n= 28), frontotemporal dementia (bvFTD, n= 35) …
astroglial GFAP in patients with AD (n= 28), frontotemporal dementia (bvFTD, n= 35) …
[HTML][HTML] Plasma GFAP in Parkinson's disease with cognitive impairment and its potential to predict conversion to dementia
Y Tang, L Han, S Li, T Hu, Z Xu, Y Fan, X Liang… - npj Parkinson's …, 2023 - nature.com
Glial fibrillary acidic protein (GFAP) has been suggested as a biomarker for reactive
astrogliosis. We measured the levels of plasma GFAP by Simoa in 60 patients with PD with …
astrogliosis. We measured the levels of plasma GFAP by Simoa in 60 patients with PD with …
Glial fibrillar acidic protein in the cerebrospinal fluid of Alzheimer's disease, dementia with Lewy bodies, and frontotemporal lobar degeneration
A Ishiki, M Kamada, Y Kawamura… - Journal of …, 2016 - Wiley Online Library
Biomarkers in the cerebrospinal fluid (CSF) are currently regarded as indispensable
indicators for accurate differential diagnosis of neurodegenerative disorders. Although high …
indicators for accurate differential diagnosis of neurodegenerative disorders. Although high …
Serum GFAP differentiates Alzheimer's disease from frontotemporal dementia and predicts MCI-to-dementia conversion
P Oeckl, S Anderl-Straub, CAF Von Arnim… - Journal of Neurology …, 2022 - jnnp.bmj.com
Objective Reactive astrogliosis is a hallmark of Alzheimer's disease (AD) and frontotemporal
dementia (FTD) but differences between the diseases and time course are unclear. Here, we …
dementia (FTD) but differences between the diseases and time course are unclear. Here, we …
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