Differences between plasma and cerebrospinal fluid glial fibrillary acidic protein levels across the Alzheimer disease continuum

AL Benedet, M Milà-Alomà, A Vrillon, NJ Ashton… - JAMA …, 2021 - jamanetwork.com
Importance Glial fibrillary acidic protein (GFAP) is a marker of reactive astrogliosis that
increases in the cerebrospinal fluid (CSF) and blood of individuals with Alzheimer disease …

Plasma glial fibrillary acidic protein in the Alzheimer disease continuum: relationship to other biomarkers, differential diagnosis, and prediction of clinical progression

XN Shen, SY Huang, M Cui, QH Zhao, Y Guo… - Clinical …, 2023 - academic.oup.com
Background Plasma glial fibrillary acidic protein (GFAP) has emerged as a promising
biomarker in neurological disorders, but further evidence is required in relation to its …

[HTML][HTML] Plasma glial fibrillary acidic protein detects Alzheimer pathology and predicts future conversion to Alzheimer dementia in patients with mild cognitive …

C Cicognola, S Janelidze, J Hertze… - Alzheimer's research & …, 2021 - Springer
Introduction Plasma glial fibrillary acidic protein (GFAP) is a marker of astroglial activation
and astrocytosis. We assessed the ability of plasma GFAP to detect Alzheimer's disease …

Plasma glial fibrillary acidic protein levels differ along the spectra of amyloid burden and clinical disease stage

BM Asken, FM Elahi, R La Joie, A Strom… - Journal of …, 2020 - content.iospress.com
Background: Measuring plasma glial fibrillary acidic protein (GFAP) alongside cortical
amyloid-β (Aβ) may shed light on astrocytic changes in aging and Alzheimer's disease (AD) …

Differences between blood and cerebrospinal fluid glial fibrillary Acidic protein levels: The effect of sample stability

J Simrén, H Weninger, WS Brum, S Khalil… - Alzheimer's & …, 2022 - Wiley Online Library
Introduction Recent evidence has shown that the marker of reactive astrogliosis, glial
fibrillary acidic protein (GFAP), has a stronger relationship with cerebral amyloid beta (Aβ) …

[HTML][HTML] Plasma glial fibrillary acidic protein is elevated in cognitively normal older adults at risk of Alzheimer's disease

P Chatterjee, S Pedrini, E Stoops, K Goozee… - Translational …, 2021 - nature.com
Glial fibrillary acidic protein (GFAP), an astrocytic cytoskeletal protein, can be measured in
blood samples, and has been associated with Alzheimer's disease (AD). However, plasma …

Glial fibrillary acidic protein in serum is increased in Alzheimer's disease and correlates with cognitive impairment

P Oeckl, S Halbgebauer… - Journal of …, 2019 - content.iospress.com
Reliable blood biomarkers for Alzheimer's disease (AD) are missing. We measured
astroglial GFAP in patients with AD (n= 28), frontotemporal dementia (bvFTD, n= 35) …

[HTML][HTML] Plasma GFAP in Parkinson's disease with cognitive impairment and its potential to predict conversion to dementia

Y Tang, L Han, S Li, T Hu, Z Xu, Y Fan, X Liang… - npj Parkinson's …, 2023 - nature.com
Glial fibrillary acidic protein (GFAP) has been suggested as a biomarker for reactive
astrogliosis. We measured the levels of plasma GFAP by Simoa in 60 patients with PD with …

Glial fibrillar acidic protein in the cerebrospinal fluid of Alzheimer's disease, dementia with Lewy bodies, and frontotemporal lobar degeneration

A Ishiki, M Kamada, Y Kawamura… - Journal of …, 2016 - Wiley Online Library
Biomarkers in the cerebrospinal fluid (CSF) are currently regarded as indispensable
indicators for accurate differential diagnosis of neurodegenerative disorders. Although high …

Serum GFAP differentiates Alzheimer's disease from frontotemporal dementia and predicts MCI-to-dementia conversion

P Oeckl, S Anderl-Straub, CAF Von Arnim… - Journal of Neurology …, 2022 - jnnp.bmj.com
Objective Reactive astrogliosis is a hallmark of Alzheimer's disease (AD) and frontotemporal
dementia (FTD) but differences between the diseases and time course are unclear. Here, we …