Diagnosis and treatment of culture-negative periprosthetic joint infection

GS Goh, J Parvizi - The Journal of Arthroplasty, 2022 - Elsevier
Identification of the causative organism (s) in periprosthetic joint infection (PJI) is a
challenging task. The shortcomings of traditional cultures have been emphasized in recent …

Culture-negative periprosthetic joint infection: is there a diagnostic role for next-generation sequencing?

K Goswami, J Parvizi - Expert Review of Molecular Diagnostics, 2020 - Taylor & Francis
Periprosthetic joint infection (PJI) following joint arthroplasty is a devastating complication.
Despite recent advances in prevention, infection remains a real challenge and an important …

Diagnosis of periprosthetic joint infection: the potential of next-generation sequencing

M Tarabichi, N Shohat, K Goswami, A Alvand… - Jbjs, 2018 - journals.lww.com
Background: Next-generation sequencing is a well-established technique for sequencing of
DNA and has recently gained attention in many fields of medicine. Our aim was to evaluate …

An enhanced understanding of culture-negative periprosthetic joint infection with next-generation sequencing: a multicenter study

K Goswami, S Clarkson, CD Phillips, DA Dennis… - JBJS, 2022 - journals.lww.com
Background: The challenges of culture-negative periprosthetic joint infection (PJI) have led
to the emergence of molecular methods of pathogen identification, including next-generation …

Culturing periprosthetic joint infection: number of samples, growth duration, and organisms

MM Kheir, TL Tan, CT Ackerman, R Modi, C Foltz… - The Journal of …, 2018 - Elsevier
Background Owing to the difficulty isolating microorganisms in periprosthetic joint infection
(PJI), current guidelines recommend that 3-5 intraoperative samples be cultured and …

Low-virulence organisms and periprosthetic joint infection—biofilm considerations of these organisms

KK Boyle, S Wood, TD Tarity - Current Reviews in Musculoskeletal …, 2018 - Springer
Abstract Purpose of Review The purpose of this manuscript is to provide a critical review of
peer-reviewed literature over the last 5 years related to low virulent organisms associated …

Culture-negative periprosthetic joint infection: prevalence, aetiology, evaluation, recommendations, and treatment

I Kalbian, JW Park, K Goswami, YK Lee… - International …, 2020 - Springer
Purpose Periprosthetic joint infection (PJI) is a catastrophic complication after total joint
arthroplasty (TJA). Treatment of PJI is challenging, especially when causative …

Advances in the laboratory diagnosis of prosthetic joint infection

A Trampuz, JM Steckelberg, DR Osmon… - … and Research in …, 2003 - journals.lww.com
Prosthetic joint implant surgery (arthroplasty) provides restoration of movement to almost
half a million people each year in the USA, with major health and economic benefits. While …

Culture-negative periprosthetic joint infections

J Palan, C Nolan, K Sarantos… - EFORT open …, 2019 - eor.bioscientifica.com
Culture-negative periprosthetic joint infections (CN-PJI) pose a significant challenge in terms
of diagnosis and management. The reported incidence of CN-PJI is reported to be between …

[HTML][HTML] A review of the literature on culture-negative periprosthetic joint infection: epidemiology, diagnosis and treatment

HK Yoon, SH Cho, DY Lee, BH Kang… - Knee surgery & …, 2017 - ncbi.nlm.nih.gov
Purpose The prevalence of periprosthetic joint infection (PJI) has increased with the
increasing incidence of arthroplasty surgery. Considering identification of causative …