[HTML][HTML] Cytotoxic synergism of Clostridioides difficile toxin B with proinflammatory cytokines in subjects with inflammatory bowel diseases
G Bassotti, A Fruganti, F Stracci, P Marconi… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Clostridioides difficile (C. difficile) is progressively colonizing humans and animals living
with humans. During this process, hypervirulent strains and mutated toxin A and B of C …
with humans. During this process, hypervirulent strains and mutated toxin A and B of C …
Proinflammatory Cytokines: Possible Accomplices for the Systemic Effects of Clostridioides difficile Toxin B
K Fettucciari, A Fruganti, A Marchegiani… - Journal of …, 2021 - Taylor & Francis
Clostridioides difficile infection (CDI) has a serious impact on the healthcare system, and
most of its pathogenic effects are mainly due to the activity of toxins A and B (TcdA and TcdB …
most of its pathogenic effects are mainly due to the activity of toxins A and B (TcdA and TcdB …
The cytotoxic synergy between Clostridioides difficile toxin B and proinflammatory cytokines: an unholy alliance favoring the onset of Clostridioides difficile infection …
G Bassotti, A Marchegiani, P Marconi… - …, 2020 - Wiley Online Library
Clostridioides difficile infection (CDI) represents an important health problem worldwide,
with significant morbidity and mortality. This infection has also high recurrence rates, whose …
with significant morbidity and mortality. This infection has also high recurrence rates, whose …
Pathogenesis of Clostridium difficile Infection and Its Potential Role in Inflammatory Bowel Disease
TM Monaghan, A Cockayne… - Inflammatory bowel …, 2015 - academic.oup.com
Colonization with toxigenic Clostridium difficile may be associated with a wide spectrum of
clinical presentation ranging from asymptomatic carriage to mild diarrhea to life-threatening …
clinical presentation ranging from asymptomatic carriage to mild diarrhea to life-threatening …
Pro-Inflammatory Cytokines Enhanced In Vitro Cytotoxic Activity of Clostridioides difficile Toxin B in Enteric Glial Cells: The Achilles Heel of Clostridioides difficile …
K Fettucciari, A Spaterna, P Marconi… - International Journal of …, 2024 - mdpi.com
Bacterial infections are characterized by an inflammatory response, which is essential for
infection containment but is also responsible for negative effects on the host. The pathogen …
infection containment but is also responsible for negative effects on the host. The pathogen …
Host Immune Response to Clostridium difficile Infection in Inflammatory Bowel Disease Patients
M Hughes, T Qazi, A Berg, J Weinberg… - Inflammatory bowel …, 2016 - academic.oup.com
Background Clostridium difficile infection (CDI) affects patients with inflammatory bowel
disease (IBD). The aim of this study was to compare humoral response to C. difficile toxins in …
disease (IBD). The aim of this study was to compare humoral response to C. difficile toxins in …
Clostridioides difficile Infection in Patients with Inflammatory Bowel Disease May be Favoured by the Effects of Proinflammatory Cytokines on the Enteroglial Network
G Bassotti, A Fruganti, G Maconi… - Journal of …, 2021 - Taylor & Francis
Clostridioides difficile infection is widespread throughout countries and represents an
important cause of nosocomial diarrhoea, with relatively high morbidity. This infection often …
important cause of nosocomial diarrhoea, with relatively high morbidity. This infection often …
The Current Knowledge on Clostridioides difficile Infection in Patients with Inflammatory Bowel Diseases
Clostridioides difficile (C. difficile) represents a major health burden with substantial
economic and clinical impact. Patients with inflammatory bowel diseases (IBD) were …
economic and clinical impact. Patients with inflammatory bowel diseases (IBD) were …
Exploring the Toxin-Mediated Mechanisms in Clostridioides difficile Infection
E Pourliotopoulou, T Karampatakis, M Kachrimanidou - Microorganisms, 2024 - mdpi.com
Clostridioides difficile infection (CDI) is the leading cause of nosocomial antibiotic-
associated diarrhea, and colitis, with increasing incidence and healthcare costs. Its …
associated diarrhea, and colitis, with increasing incidence and healthcare costs. Its …
The roles of host and pathogen factors and the innate immune response in the pathogenesis of Clostridium difficile infection
X Sun, SA Hirota - Molecular immunology, 2015 - Elsevier
Clostridium difficile (C. difficile) is the most common cause of nosocomial antibiotic-
associated diarrhea and the etiologic agent of pseudomembranous colitis. The clinical …
associated diarrhea and the etiologic agent of pseudomembranous colitis. The clinical …