Oral insulin delivery platforms: strategies to address the biological barriers
Diabetes mellitus is a lifelong metabolic disease that requires frequent subcutaneous
injections of insulin. However, this method of administration can be associated with patient …
injections of insulin. However, this method of administration can be associated with patient …
Emerging micro-and nanotechnology based synthetic approaches for insulin delivery
Insulin is essential for type 1 and advanced type 2 diabetics to maintain blood glucose levels
and prolong lives. The traditional administration requires frequent subcutaneous insulin …
and prolong lives. The traditional administration requires frequent subcutaneous insulin …
Versatile oral insulin delivery nanosystems: from materials to nanostructures
M Wang, C Wang, S Ren, J Pan, Y Wang… - International Journal of …, 2022 - mdpi.com
Diabetes is a chronic metabolic disease characterized by lack of insulin in the body leading
to failure of blood glucose regulation. Diabetes patients usually need frequent insulin …
to failure of blood glucose regulation. Diabetes patients usually need frequent insulin …
Oral insulin delivery: how far are we?
Oral delivery of insulin may significantly improve the quality of life of diabetes patients who
routinely receive insulin by the subcutaneous route. In fact, compared with this …
routinely receive insulin by the subcutaneous route. In fact, compared with this …
Oral insulin delivery: existing barriers and current counter-strategies
A Gedawy, J Martinez, H Al-Salami… - Journal of pharmacy …, 2018 - academic.oup.com
Objectives The chronic and progressive nature of diabetes is usually associated with micro-
and macrovascular complications where failure of pancreatic β-cell function and a general …
and macrovascular complications where failure of pancreatic β-cell function and a general …
[PDF][PDF] Glucose-responsive oral insulin delivery platform for one treatment a day in diabetes
Oral delivery of insulin is of great convenience in treating diabetes but is still subject to the
harsh gastrointestinal tract. Herein, we developed an intelligent oral insulin platform based …
harsh gastrointestinal tract. Herein, we developed an intelligent oral insulin platform based …
An overview of oral insulin delivery strategies (OIDS)
Despite tremendous efforts, the world continues its fight against the common chronic
disease-diabetes. Diabetes is caused by elevated glucose levels in the blood, which can …
disease-diabetes. Diabetes is caused by elevated glucose levels in the blood, which can …
Insulin administration: present strategies and future directions for a noninvasive (possibly more physiological) delivery
E Matteucci, O Giampietro, V Covolan… - Drug Design …, 2015 - Taylor & Francis
Insulin is a life-saving medication for people with type 1 diabetes, but traditional insulin
replacement therapy is based on multiple daily subcutaneous injections or continuous …
replacement therapy is based on multiple daily subcutaneous injections or continuous …
Advances in buccal and oral delivery of insulin
Diabetes mellitus is a metabolic endocrine disease characterized by chronic hyperglycemia
with disturbances in metabolic processes, such as those related to carbohydrates, fat, and …
with disturbances in metabolic processes, such as those related to carbohydrates, fat, and …
Oral insulin delivery
GP Carino, E Mathiowitz - Advanced drug delivery reviews, 1999 - Elsevier
An oral form of insulin has been the elusive goal for many investigators since the protein's
initial discovery by Banting and Best in 1922. This paper will attempt to answer why this is …
initial discovery by Banting and Best in 1922. This paper will attempt to answer why this is …