Position-dependent sequence elements downstream of AAUAAA are required for efficient rabbit β-globin mRNA 3′ end formation
A Gil, NJ Proudfoot - Cell, 1987 - cell.com
We previously demonstrated that a critical 35 bp region 3'of the AAUAAA is required for
rabbit (3-globln mRNA 3'end formation. Recently, we synthesized and tested sequence …
rabbit (3-globln mRNA 3'end formation. Recently, we synthesized and tested sequence …
A sequence downstream of AAUAAA is required for rabbit β-globin mRNA 3′-end formation
A Gil, NJ Proudfoot - Nature, 1984 - nature.com
Abstract The sequence AAUAAA, found 11–30 base pairs (bp) upstream of the poly (A) site
of most non-histone eukaryotic messenger RNAs (mRNAs) 1 forms an essential part of the …
of most non-histone eukaryotic messenger RNAs (mRNAs) 1 forms an essential part of the …
Definition of an efficient synthetic poly (A) site.
N Levitt, D Briggs, A Gil, NJ Proudfoot - Genes & development, 1989 - genesdev.cshlp.org
We constructed and analyzed a synthetic poly (A)(SPA) site that was based on the highly
efficient poly (A) signal of the rabbit beta-globin gene. By use of the SPA, we demonstrate …
efficient poly (A) signal of the rabbit beta-globin gene. By use of the SPA, we demonstrate …
Several Distinct Types of Sequence Elements Are Required for Efficient mRNA 3′ End Formation in a Pea rbcS Gene
BD Mogen, MH Macdonald, G Leggewie… - Molecular and cellular …, 1992 - Taylor & Francis
We have conducted an extensive linker substitution analysis of the polyadenylation signal
from a pea rbcS gene. From these studies, we can identify at least two, and perhaps three …
from a pea rbcS gene. From these studies, we can identify at least two, and perhaps three …
Poly A sequences at the 3′ termini of rabbit globin mRNAs
H BURR, JB LINGREL - Nature New Biology, 1971 - nature.com
Time after infection (h) Page 1 NATURE NEW BIOLOGY VOL. 233 SEPTEMBER 8 1971 4 %
Table 2 Effect of SV40 and 5-Fluoro 2-deoxyuridine (FUdR) Addition on Autoradiography …
Table 2 Effect of SV40 and 5-Fluoro 2-deoxyuridine (FUdR) Addition on Autoradiography …
[HTML][HTML] A novel function for the U2AF 65 splicing factor in promoting pre‐mRNA 3′‐end processing
S Millevoi, F Geraghty, B Idowu, JLY Tam… - EMBO …, 2002 - embopress.org
Abstract Splicing and 3′‐end processing (including cleavage and polyadenylation) of
vertebrate pre‐mRNAs are tightly coupled events that contribute to the extensive molecular …
vertebrate pre‐mRNAs are tightly coupled events that contribute to the extensive molecular …
Molecular mechanisms of eukaryotic pre-mRNA 3′ end processing regulation
S Millevoi, S Vagner - Nucleic acids research, 2010 - academic.oup.com
ABSTRACT Messenger RNA (mRNA) 3′ end formation is a nuclear process through which
all eukaryotic primary transcripts are endonucleolytically cleaved and most of them acquire a …
all eukaryotic primary transcripts are endonucleolytically cleaved and most of them acquire a …
Recent molecular insights into canonical pre-mRNA 3'-end processing
The majority of eukaryotic messenger RNA precursors (pre-mRNAs) undergo cleavage and
polyadenylation at their 3′ end. This canonical 3′-end processing depends on sequence …
polyadenylation at their 3′ end. This canonical 3′-end processing depends on sequence …
Do the poly (A) tail and 3′ untranslated region control mRNA translation?
RJ Jackson, N Standart - Cell, 1990 - Elsevier
From the date of its discovery in 1970, the 3'poly (A) tail of eukaryotic mRNA has taken on
the character of a structure in search of a function. Candidate functions favored in those far …
the character of a structure in search of a function. Candidate functions favored in those far …
Eukaryotic mRNA 3′ processing: a common means to different ends
GM Gilmartin - Genes & development, 2005 - genesdev.cshlp.org
In principle, the formation of the 3 end of a eukaryotic mRNA is a simple process. At a
minimum, it involves the hydrolysis of a single phosphodiester bond in the nascent …
minimum, it involves the hydrolysis of a single phosphodiester bond in the nascent …