Background Dysregulated bile acid (BA) metabolism has been linked to steatosis,
inflammation, and fibrosis in nonalcoholic fatty liver disease (NAFLD). Aim To determine …

METHODS: We collected stool samples from 287 participants from 5 hospitals in Japan
(healthy control [HC]: n= 88; mild fibrosis: n= 104; and advanced fibrosis group: n= 95) …

Abstract Background Bile acids (BAs) are synthesized by the liver and modified by gut
bacteria, and may play an intermediary role between the gut microbiome and liver in …

Objective Metabolomic studies suggest plasma levels of bile acids (BAs) are elevated
amongst subjects with non-alcoholic fatty liver disease (NAFLD) compared to healthy …

Abstract Background and Aims Bile acid (BA) dysregulation is related to not only metabolic
diseases but also nonalcoholic fatty liver disease (NAFLD). We investigated whether …

Background & Aims Non-alcoholic fatty liver disease (NAFLD) is characterized by dysbiosis.
The bidirectional effects between intestinal microbiota (IM) and bile acids (BA) suggest that …

Background The fasting‐state serum bile acid profile in nonalcoholic fatty liver disease
(NAFLD) has been reported to differ when nonalcoholic steatohepatitis is compared to …

Background Non-alcoholic fatty liver disease (NAFLD) is currently the major cause of
chronic liver disease globally. Bile acids (BAs) have emerged as relevant signaling …

Purpose The identification of significant fibrosis is critical for predicting the prognosis of non-
alcoholic fatty liver disease (NAFLD). This study aimed to compare the predictive value of …

Context Guidelines recommend blood-based fibrosis biomarkers to identify advanced
nonalcoholic fatty liver disease (NAFLD), which is particularly prevalent in patients with …