The relative electrophoretic mobility of apo (a) isoforms depends on the gel system: proposal of a nomenclature for apo (a) phenotypes

HG Kraft, A Lingenhel, G Bader, GM Kostner… - Atherosclerosis, 1996 - Elsevier
Genetic apo (a) isoforms were originally defined according to their relative mobility in SDS-
PAGE compared to apoB-100 and were designated as F, B or S1–S4 isotypes. This widely …

Different apoprotein (a) isoform proportions in serum and carotid plaque

G Baldo, S Giunco, D Kontothanassis, MR Baiocchi… - Atherosclerosis, 2007 - Elsevier
INTRODUCTION: Cardio-and/or cerebro-vascular risk are associated with high lipoprotein
(a)[Lp (a)] levels and low-molecular-weight (LMW) apo (a) isoforms. Aims of this study were …

A novel kringle-4 number-based recombinant apo [a] standard for human apo [a] phenotyping

E Anglés-Cano, S Loyau, G Cardoso-Saldana… - Journal of lipid …, 1999 - ASBMB
Apolipoprotein [a] phenotyping is a critically important method to explore the role of kringle-4
repeat number as a modulator of lipoprotein [a]-associated cardiovascular risk. The …

Apolipoprotein (a): A comparison of isoforms identified by sodium dodecyl sulfate‐polyacrylamide gel electrophoresis or by sodium dodecyl sulfate‐agarose gel …

WY Craig, SE Poulin, TB Ledue, MI Kamboh - Electrophoresis, 1993 - Wiley Online Library
Lipoprotein (a) resembles low density lipoprotein in structure, except that a unique
apolipoprotein (apo), apo (a), is linked to apo B‐100. Variations in the number of sequence …

Characterization of apo (a) polymorphism by a modified immunoblotting technique in an Italian population sample

D Geroldi, V Bellotti, P Buscaglia, G Bonetti… - Clinica chimica acta, 1993 - Elsevier
Apo (a), the specific lipoprotein (a)(Lp (a)) apolipoprotein, is characterized by different
isoforms (from 6 to 11 on SDS-PAGE) encoded by a system of autosomal codominant …

Relation between number of apolipoprotein (a) kringle 4 repeats and mobility of isoforms in agarose gel: basis for a standardized isoform nomenclature

SM Marcovina, HH Hobbs, JJ Albers - Clinical chemistry, 1996 - academic.oup.com
The size of apolipoprotein (a)[apo (a)] varies from 187 to 648 kDa because of interallelic
differences in the number of kringle 4-encoding sequences in the apo (a) gene. Plasma apo …

Molecular analysis of apo (a) fragmentation in polygenic hypercholesterolemia: characterization of a new plasma fragment pattern

S Gonbert, B Saint-Jore, P Giral, C Doucet… - … , and vascular biology, 2001 - Am Heart Assoc
Hypercholesterolemia is frequently associated with elevated Lp (a) levels, an independent
risk factor for coronary, cerebrovascular, and peripheral vascular disease. A portion of …

Apo (a) isoforms predict risk for coronary heart disease. A study in six populations.

C Sandholzer, N Saha, JD Kark, A Rees… - … and thrombosis: a …, 1992 - Am Heart Assoc
Elevated concentrations of lipoprotein (a)(Lp [a]) in plasma are associated with premature
coronary heart disease (CHD). Lp (a) levels are largely determined by alleles at the …

Apo (a) isoforms do not predict risk for coronary heart disease in a Gulf Arab population

AO Akanji - Annals of clinical biochemistry, 2000 - journals.sagepub.com
It is well recognized that blood lipoprotein A [Lp (a)] levels constitute an important risk factor
for atherosclerotic vascular disease. In some populations, mainly Caucasian, Lp (a) levels …

Contribution of apolipoprotein (a) size, pentanucleotide TTTTA repeat and C/T (+ 93) polymorphisms of the apo (a) gene to regulation of lipoprotein (a) plasma levels …

K Valenti, E Aveynier, S Leauté, F Laporte, AJ Hadjian - Atherosclerosis, 1999 - Elsevier
Several studies indicate that the inter-individual variation in plasma concentrations of
lipoprotein (a)(Lp (a)) is mainly under genetic control. To define the effect of three DNA …