Acetaminophen (APAP) overdose has long been considered a major cause of drug-induced
liver injury. Ferroptosis is a type of programmed cell death mediated by iron-dependent lipid …

Acetaminophen (APAP) overdose has been considered responsible for the drug-induced
liver injury for many years. Ferroptosis is defined as an iron-dependent form of cell death …

Acetaminophen (APAP) overdose is a common cause of drug-induced acute liver failure.
Although hepatocyte cell death is considered to be the critical event in APAP-induced …

Acetaminophen (APAP)-induced liver injury (AILI) has become a growing public health
problem. Ferroptosis, an iron-dependent form of cell death associated with lipid peroxide …

Acetaminophen (APAP) overdose-induced hepatotoxicity is the most common cause of drug-
induced liver injury worldwide, which is significantly linked to oxidative stress and sterile …

Abietic acid has been known to exhibit anti-inflammatory activity. This study was designed to
investigate the protective effects of abietic acid on acetaminophen (APAP)-induced liver …

We read with great interest the review article by which Jaeschke et al.(2019) in which the
authors thoroughly reviewed the forms of cell death in acetaminophen (APAP)-induced …

Acetaminophen (APAP) overdose is a common cause of drug-induced liver injury (DILI).
Ferroptosis has been recently implicated in APAP-induced liver injury (AILI). However, the …

Farrerol has been shown to have antioxidative potential via Nrf2 activation, which in turn is
involved in the prevention of hepatotoxicity. The purpose of the current study was to explore …

Drug-induced liver injury is the major cause of acute liver failure. However, the underlying
mechanisms seem to be multifaceted and remain poorly understood, resulting in few …