The hepatic microcirculation: mechanistic contributions and therapeutic targets in liver injury and repair
B Vollmar, MD Menger - Physiological reviews, 2009 - journals.physiology.org
The complex functions of the liver in biosynthesis, metabolism, clearance, and host defense
are tightly dependent on an adequate microcirculation. To guarantee hepatic homeostasis …
are tightly dependent on an adequate microcirculation. To guarantee hepatic homeostasis …
Role of microcirculation in hepatic ischemia/reperfusion injury.
MD Menger, S Richter, J Yamauchi… - Hepato …, 1999 - europepmc.org
There is a large body of evidence that the liver microcirculation has to be considered as a
major target in hepatic ischemia/reperfusion injury. The nature of microvascular injury, which …
major target in hepatic ischemia/reperfusion injury. The nature of microvascular injury, which …
Liver perfusion in sepsis, septic shock, and multiorgan failure
H Spapen - The Anatomical Record: Advances in Integrative …, 2008 - Wiley Online Library
Sepsis causes significant alterations in the hepatic macro‐and microcirculation. Diverging
views exist on global hepatic blood flow during experimental sepsis because of the large …
views exist on global hepatic blood flow during experimental sepsis because of the large …
[PDF][PDF] Vascular mediators in the injured liver
DC Rockey - Hepatology, 2003 - Wiley Online Library
The vasculature plays a critical role in multiple physiologic and pathophysiologic processes.
A number of recent advances have led to renewed focus on the vasculature in the liver. In …
A number of recent advances have led to renewed focus on the vasculature in the liver. In …
Hepatic microcirculation and mechanisms of portal hypertension
J Gracia-Sancho, G Marrone… - Nature reviews …, 2019 - nature.com
The liver microcirculatory milieu, mainly composed of liver sinusoidal endothelial cells
(LSECs), hepatic stellate cells (HSCs) and hepatic macrophages, has an essential role in …
(LSECs), hepatic stellate cells (HSCs) and hepatic macrophages, has an essential role in …
Hemorheological and microcirculatory factors in liver ischemia-reperfusion injury—An update on pathophysiology, molecular mechanisms and protective strategies
Hepatic ischemia-reperfusion injury (IRI) is a multifactorial phenomenon which has been
associated with adverse clinical outcomes. IRI related tissue damage is characterized by …
associated with adverse clinical outcomes. IRI related tissue damage is characterized by …
Hepatic ischemia reperfusion injury: pathogenic mechanisms and basis for hepatoprotection
NC Teoh, GC Farrell - Journal of gastroenterology and …, 2003 - Wiley Online Library
This review highlights recent advances in our understanding of mechanisms underlying
reperfusion injury to the liver after warm hepatic ischemia. Sinusoidal endothelial cells and …
reperfusion injury to the liver after warm hepatic ischemia. Sinusoidal endothelial cells and …
The hepatic microvascular responses to sepsis
A Ring, W Stremmel - Seminars in thrombosis and hemostasis, 2000 - thieme-connect.com
The liver is believed to play a major role in the initiation of multiorgan failure, the most lethal
complication in the clinical course of sepsis. Microbes and their virulence factors enter the …
complication in the clinical course of sepsis. Microbes and their virulence factors enter the …
[PDF][PDF] Liver ischemia/reperfusion injury: processes in inflammatory networks—a review
M Abu‐Amara, SY Yang, N Tapuria, B Fuller… - Liver …, 2010 - Wiley Online Library
Liver ischemia/reperfusion (IR) injury is typified by an inflammatory response.
Understanding the cellular and molecular events underpinning this inflammation is …
Understanding the cellular and molecular events underpinning this inflammation is …
[HTML][HTML] Vascular pathobiology in chronic liver disease and cirrhosis–current status and future directions
Y Iwakiri, V Shah, DC Rockey - Journal of hepatology, 2014 - Elsevier
Chronic liver disease is associated with remarkable alterations in the intra-and extrahepatic
vasculature. Because of these changes, the fields of liver vasculature and portal …
vasculature. Because of these changes, the fields of liver vasculature and portal …
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