Neuroprotective and neurorescue effects of a novel polymeric nanoparticle formulation of curcumin (NanoCurc™) in the neuronal cell culture and animal model …

B Ray, S Bisht, A Maitra, A Maitra… - Journal of Alzheimer's …, 2011 - content.iospress.com
Alzheimer's disease (AD) is characterized by deposition of amyloid-β (Aβ) plaques within the
brain parenchyma followed by synaptic loss and neuronal death. Deposited Aβ reacts with …

Neuronal uptake and neuroprotective effect of curcumin-loaded PLGA nanoparticles on the human SK-N-SH cell line

S Doggui, JK Sahni, M Arseneault… - Journal of …, 2012 - content.iospress.com
Curcumin, a natural polyphenolic pigment present in the spice turmeric (Curcuma longa), is
known to possess a pleiotropic activity such as antioxidant, anti-inflammatory, and anti …

Highly Stabilized Curcumin Nanoparticles Tested in an In Vitro Blood–Brain Barrier Model and in Alzheimer's Disease Tg2576 Mice

KK Cheng, CF Yeung, SW Ho, SF Chow, AHL Chow… - The AAPS journal, 2013 - Springer
The therapeutic effects of curcumin in treating Alzheimer's disease (AD) depend on the
ability to penetrate the blood–brain barrier. The latest nanoparticle technology can help to …

Neuroprotective properties of curcumin in Alzheimer's disease-merits and limitations

D Chin, P Huebbe, K Pallauf… - Current medicinal …, 2013 - ingentaconnect.com
As demographics in developed nations shift towards an aging population,
neurodegenerative pathologies, especially dementias such as Alzheimer's disease, pose …

Application of curcumin nanoformulations in Alzheimer's disease: prevention, diagnosis and treatment

H Lv, Y Wang, X Yang, G Ling, P Zhang - Nutritional neuroscience, 2023 - Taylor & Francis
Objectives: Alzheimer's disease (AD) is a serious neurodegenerative disease. Although
many therapeutic strategies have been studied, their clinical applications are immature …

The impact of curcumin and its modified formulations on Alzheimer's disease

T Farkhondeh, S Samarghandian… - Journal of cellular …, 2019 - Wiley Online Library
Alzheimer's disease (AD) is a major health problem worldwide, with no effective treatment
approach. Curcumin is the main ingredient of turmeric traditionally used in Asian medicine …

Curcumin formulations and trials: what's new in neurological diseases

S Gagliardi, C Morasso, P Stivaktakis, C Pandini… - Molecules, 2020 - mdpi.com
Curcumin's pharmacological properties and its possible benefits for neurological diseases
and dementia have been much debated. In vitro experiments show that curcumin modulates …

Curcuminoids enhance memory in an amyloid-infused rat model of Alzheimer's disease

T Ahmed, SA Enam, AH Gilani - Neuroscience, 2010 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disease. There are a limited number of
therapeutic options available for the treatment of AD. Curcuminoids (a mixture of …

Curcumin-loaded nanoparticles: A novel therapeutic strategy in treatment of central nervous system disorders

H Yavarpour-Bali, M Ghasemi-Kasman… - International journal of …, 2019 - Taylor & Francis
Curcumin as a hydrophobic polyphenol is extracted from the rhizome of Curcuma longa.
Curcumin is widely used as a dietary spice and a topical medication for the treatment of …

Curcumin's nanomedicine formulations for therapeutic application in neurological diseases

B Salehi, D Calina, AO Docea, N Koirala… - Journal of Clinical …, 2020 - mdpi.com
The brain is the body's control center, so when a disease affects it, the outcomes are
devastating. Alzheimer's and Parkinson's disease, and multiple sclerosis are brain diseases …