Background & Aims Autophagy plays a crucial role in hepatic homeostasis and its
deregulation has been associated with chronic liver disease. However, the effect of …

Liver fibrosis is characterized by the activation and migration of hepatic stellate cells (HSCs),
followed by matrix deposition. Recently, several studies have shown the importance of …

Liver fibrosis (LF) occurs as a result of persistent liver injury and can be defined as a
pathologic, chronic, wound‐healing process in which functional parenchyma is …

BACKGROUND & AIMS: Autophagy is a metabolic process that degrades and recycles
intracellular organelles and proteins with many connections to human disease and …

BACKGROUND & AIMS: The pathogenesis of liver fibrosis involves activation of hepatic
stellate cells, which is associated with depletion of intracellular lipid droplets. When …

Liver fibrosis is a common wound healing response to chronic liver injury of all causes, and
its end‐stage cirrhosis is responsible for high morbidity and mortality worldwide. Fibrosis …

The pathogenesis of liver fibrosis in nonalcoholic fatty liver disease (NAFLD) remains
unclear and the effective treatments have not been explored yet. The activation of hepatic …

Hepatic fibrosis is a pathological lesion, characterized by the progressive accumulation of
extracellular matrix (ECM) in the perisinusoidal space and it is a major problem in chronic …

Activation of hepatic stellate cells (HSC), a resident pericytic cell in liver, into a proliferative
and fibrogenic cell type, is the principal event underlying hepatic fibrosis following injury …

Activation of hepatic stellate cells (HSCs) is a pivotal event in liver fibrosis, characterized by
dramatic disappearance of lipid droplets (LDs). Although LD disappearance has long been …