CellRank 2: unified fate mapping in multiview single-cell data
Single-cell RNA sequencing allows us to model cellular state dynamics and fate decisions
using expression similarity or RNA velocity to reconstruct state-change trajectories; however …
using expression similarity or RNA velocity to reconstruct state-change trajectories; however …
Unified fate mapping in multiview single-cell data
Single-cell RNA sequencing allows us to model cellular state dynamics and fate decisions
using expression similarity or RNA velocity to reconstruct state-change trajectories …
using expression similarity or RNA velocity to reconstruct state-change trajectories …
Characterization of cell fate probabilities in single-cell data with Palantir
Single-cell RNA sequencing studies of differentiating systems have raised fundamental
questions regarding the discrete versus continuous nature of both differentiation and cell …
questions regarding the discrete versus continuous nature of both differentiation and cell …
Deciphering cell fate decision by integrated single-cell sequencing analysis
Sagar, D Grün - Annual review of biomedical data science, 2020 - annualreviews.org
Cellular differentiation is a common underlying feature of all multicellular organisms through
which naïve cells progressively become fate restricted and develop into mature cells with …
which naïve cells progressively become fate restricted and develop into mature cells with …
CellRank for directed single-cell fate mapping
Computational trajectory inference enables the reconstruction of cell state dynamics from
single-cell RNA sequencing experiments. However, trajectory inference requires that the …
single-cell RNA sequencing experiments. However, trajectory inference requires that the …
[PDF][PDF] Untangling biological factors influencing trajectory inference from single cell data
M Charrout, MJT Reinders… - NAR genomics and …, 2020 - academic.oup.com
Advances in single-cell RNA sequencing over the past decade has shifted the discussion of
cell identity toward the transcriptional state of the cell. While the incredible resolution …
cell identity toward the transcriptional state of the cell. While the incredible resolution …
[HTML][HTML] Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM
Single-cell transcriptomic assays have enabled the de novo reconstruction of lineage
differentiation trajectories, along with the characterization of cellular heterogeneity and state …
differentiation trajectories, along with the characterization of cellular heterogeneity and state …
Inference of cell state transitions and cell fate plasticity from single-cell with MARGARET
Despite recent advances in inferring cellular dynamics using single-cell RNA-seq data,
existing trajectory inference (TI) methods face difficulty in accurately reconstructing the cell …
existing trajectory inference (TI) methods face difficulty in accurately reconstructing the cell …
Generative modeling of single-cell population time series for inferring cell differentiation landscapes
GHT Yeo, SD Saksena, DK Gifford - BioRxiv, 2020 - biorxiv.org
Existing computational methods that use single-cell RNA-sequencing for cell fate prediction
either summarize observations of cell states and their couplings without modeling the …
either summarize observations of cell states and their couplings without modeling the …
Single-cell transcriptional diversity is a hallmark of developmental potential
GS Gulati, SS Sikandar, DJ Wesche, A Manjunath… - Science, 2020 - science.org
Single-cell RNA sequencing (scRNA-seq) is a powerful approach for reconstructing cellular
differentiation trajectories. However, inferring both the state and direction of differentiation is …
differentiation trajectories. However, inferring both the state and direction of differentiation is …