Is Icatibant Safe for the Treatment of Hereditary Angioedema During Pregnancy?

DV Šimac, T Štimac, S Novak - Current Allergy and Asthma Reports, 2022 - Springer
Abstract Purpose of Review Hereditary angioedema (HAE) is a disorder affecting bradykinin
regulation presenting as recurrent cutaneous or mucosal swelling. Treatment options …

Multiple doses of icatibant used during pregnancy

LW Kaminsky, T Kelbel, F Ansary… - Allergy & …, 2017 - journals.sagepub.com
Background Hereditary angioedema (HAE) is a life-long disease that often manifests by
puberty. Treatment of attacks is essential to improve quality of life and to decrease morbidity …

Treatment of hereditary angioedema attacks with icatibant and recombinant C1 inhibitor during pregnancy

R Hakl, P Kuklínek, I Krčmová, P Králíčková… - Journal of clinical …, 2018 - Springer
Purpose Hereditary angioedema (HAE) is a rare disease caused by a C1 inhibitor (C1-INH)
deficit. Clinically, HAE is manifested by repeated episodes of localized subcutaneous or …

Experience with intravenous plasma-derived C1-inhibitor in pregnant women with hereditary angioedema: a systematic literature review

JP Brooks, C Radojicic, MA Riedl… - The Journal of Allergy …, 2020 - Elsevier
Consensus guidelines recommend plasma-derived C1 inhibitor (C1-INH) as first-line
treatment in pregnant women with hereditary angioedema (HAE). We conducted a …

Safety of medications for hereditary angioedema during pregnancy and lactation

A Yeich, A Elhatw, Z Ashoor, K Park… - Expert Opinion on Drug …, 2023 - Taylor & Francis
ABSTRACT Introduction Hereditary Angioedema (HAE) attacks show an increased
frequency and severity for pregnant and lactating females secondary to the hormonal …

[HTML][HTML] Successful treatment with Cinryze® replacement therapy of a pregnant patient with hereditary angioedema: a case report

Ž Kardum, V Prus, J Milas Ahić, D Kardum - Journal of medical case …, 2021 - Springer
Background Hereditary angioedema (HAE) is a rare disease characterized with recurrent
swelling of subcutaneous or mucosal tissue that resolves in approximately 3 days. It can be …

[引用][C] Resolution of symptoms in a patient with hereditary angioedema (HAE) following treatment with icatibant, a potent and selective bradykinin-2 receptor …

T Boehm, WR Lumry - Journal of Allergy and Clinical Immunology, 2007 - jacionline.org
METHODS: HAE symptoms (mainly cutaneous and abdominal manifestations) were
documented in 3 previous generations on the maternal side of the family. The patient was …

First report of icatibant treatment in a pregnant patient with hereditary angioedema

H Farkas, KV Kőhalmi, N Veszeli… - Journal of Obstetrics …, 2016 - Wiley Online Library
Hereditary angioedema resulting from C1‐inhibitor deficiency (C1‐INH‐HAE) is a rare,
autosomal dominant disorder, characterized by recurrent attacks of edema formation. The …

[HTML][HTML] Optimum use of acute treatments for hereditary angioedema: evidence-based expert consensus

H Longhurst - Frontiers in Medicine, 2018 - frontiersin.org
Acute treatment of hereditary angioedema due to C1 inhibitor deficiency has become
available in the last 10 years and has greatly improved patients' quality of life. Two plasma …

The natural history of hereditary angioedema and the impact of treatment with human C1-inhibitor concentrate during pregnancy: a long-term survey

I Czaller, B Visy, D Csuka, G Füst, F Tóth… - European Journal of …, 2010 - Elsevier
OBJECTIVE: The course of hereditary angioedema (HAE) and the efficacy and safety of
human C1-INH concentrate were appraised during pregnancy and the postpartum period, in …