Follicular helper T (TFH) cells provide help to B cells, supporting the formation of germinal
centres that allow affinity maturation of antibody responses. Although usually located in …

Follicular helper T (TFH) cells are recently highlighted as their crucial role for humoral
immunity to infection as well as their abnormal control to induce autoimmune disease …

Follicular helper T (TFH) cells are essential for B-cell maturation and immunoglobulin
production after immunization with thymus-dependent antigens. Nevertheless, the …

T follicular helper (Tfh) cells are specialized to provide help to B cells and to induce durable
antibody response. Our knowledge on the biology of Tfh cells and their contribution to …

Background Autoimmune diseases (such as systemic lupus erythematosus, rheumatoid
arthritis, type 1 diabetes, etc) are characterized by the production of autoantibodies against …

T follicular helper (Tfh) cells are a distinct subset of CD4+ T lymphocytes, specialized in B
cell help and in regulation of antibody responses. They are required for the generation of …

Follicular helper T (Tfh) cells are one of CD4+ helper T subsets which promote B cell
maturation, activation and antigen-specific antibody production. Autoantibodies are …

The generation of protective antibodies by B cells following natural infection or vaccination
requires 'help'from CD4+ T cells. T follicular helper (Tfh) cells are the specialized CD4+ T …

CD4+ T follicular helper (Tfh) cells are recognized as a distinct T-cell subset, which provides
help for germinal center (GC) formation, B-cell development and affinity maturation, and …

Highlights•Tfh and GC response is hyperactivated in human autoimmune
diseases.•Aberrant Tfh response can be monitored by the analysis of cTfh cells.•Inflamed …