[HTML][HTML] Multimodal optical analysis discriminates freshly extracted human sample of gliomas, metastases and meningiomas from their appropriate controls
Delineating tumor margins as accurately as possible is of primordial importance in surgical
oncology: extent of resection is associated with survival but respect of healthy surrounding …
oncology: extent of resection is associated with survival but respect of healthy surrounding …
Spectral and lifetime domain measurements of rat brain tumors
D Abi Haidar, B Leh, M Zanello… - Biomedical optics express, 2015 - opg.optica.org
During glioblastoma surgery, delineation of the brain tumor margins is difficult because the
infiltrated and normal tissues have the same visual appearance. We use a fiber-optical …
infiltrated and normal tissues have the same visual appearance. We use a fiber-optical …
[HTML][HTML] Optical signatures derived from deep UV to NIR excitation discriminates healthy samples from low and high grades glioma
H Mehidine, A Chalumeau, F Poulon, F Jamme… - Scientific Reports, 2019 - nature.com
Among all the tumors of the central nervous system (CNS), glioma are the most deadly and
the most malignant. Surgical resection is the standard therapeutic method to treat this type of …
the most malignant. Surgical resection is the standard therapeutic method to treat this type of …
[HTML][HTML] Molecular changes tracking through multiscale fluorescence microscopy differentiate Meningioma grades and non-tumoral brain tissues
Meningioma is the most common primary intracranial extra-axial tumor. Total surgical
removal is the standard therapeutic method to treat this type of brain tumors. However, the …
removal is the standard therapeutic method to treat this type of brain tumors. However, the …
[HTML][HTML] Multimodal analysis of central nervous system tumor tissue endogenous fluorescence with multiscale excitation
The primary therapeutic approach for high-grade brain tumor is surgical resection. However,
identifying tumor margins in vivo remains a major challenge. Biopsy analysis remains the …
identifying tumor margins in vivo remains a major challenge. Biopsy analysis remains the …
[HTML][HTML] Real-time Brain Tumor imaging with endogenous fluorophores: a diagnosis proof-of-concept study on fresh human samples
The primary line of therapy for high-grade brain tumor is surgical resection, however,
identifying tumor margins in vivo remains a major challenge. Despite the progress in …
identifying tumor margins in vivo remains a major challenge. Despite the progress in …
Dual-modality optical biopsy of glioblastomas multiforme with diffuse reflectance and fluorescence: ex vivo retrieval of optical properties
VN Du Le, J Provias, N Murty… - … of biomedical optics, 2017 - spiedigitallibrary.org
Glioma itself accounts for 80% of all malignant primary brain tumors, and glioblastoma
multiforme (GBM) accounts for 55% of such tumors. Diffuse reflectance and fluorescence …
multiforme (GBM) accounts for 55% of such tumors. Diffuse reflectance and fluorescence …
[HTML][HTML] Optical properties, spectral, and lifetime measurements of central nervous system tumors in humans
F Poulon, H Mehidine, M Juchaux, P Varlet… - Scientific reports, 2017 - nature.com
A key challenge of central nervous system tumor surgery is to discriminate between brain
regions infiltrated by tumor cells and surrounding healthy tissue. Although monitoring of …
regions infiltrated by tumor cells and surrounding healthy tissue. Although monitoring of …
Multimodal imaging to explore endogenous fluorescence of fresh and fixed human healthy and tumor brain tissues
H Mehidine, M Sibai, F Poulon, J Pallud… - Journal of …, 2019 - Wiley Online Library
To complement a project toward label‐free optical biopsy and enhanced resection which the
overall goal is to develop a multimodal nonlinear endomicroscope, this multimodal …
overall goal is to develop a multimodal nonlinear endomicroscope, this multimodal …
Capability of physically reasonable OCT-based differentiation between intact brain tissues, human brain gliomas of different WHO grades, and glioma model 101.8 …
IN Dolganova, PV Aleksandrova, PV Nikitin… - Biomedical Optics …, 2020 - opg.optica.org
Optical coherence tomography (OCT) of the ex vivo rat and human brain tissue samples is
performed. The set of samples comprises intact white and gray matter, as well as human …
performed. The set of samples comprises intact white and gray matter, as well as human …