Inborn errors of OAS–RNase L in SARS-CoV-2–related multisystem inflammatory syndrome in children
Multisystem inflammatory syndrome in children (MIS-C) is a rare and severe condition that
follows benign COVID-19. We report autosomal recessive deficiencies of OAS1, OAS2, or …
follows benign COVID-19. We report autosomal recessive deficiencies of OAS1, OAS2, or …
Peripheral immunophenotypes in children with multisystem inflammatory syndrome associated with SARS-CoV-2 infection
Recent reports highlight a new clinical syndrome in children related to severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2)—multisystem inflammatory syndrome in …
respiratory syndrome coronavirus 2 (SARS-CoV-2)—multisystem inflammatory syndrome in …
Heterozygous OAS1 gain-of-function variants cause an autoinflammatory immunodeficiency
T Magg, T Okano, LM Koenig, DFR Boehmer… - Science …, 2021 - science.org
Analysis of autoinflammatory and immunodeficiency disorders elucidates human immunity
and fosters the development of targeted therapies. Oligoadenylate synthetase 1 is a type I …
and fosters the development of targeted therapies. Oligoadenylate synthetase 1 is a type I …
Cell-free DNA reveals distinct pathology of multisystem inflammatory syndrome in children
Multisystem inflammatory syndrome in children (MIS-C) is a rare but life-threatening
hyperinflammatory condition induced by infection with severe acute respiratory syndrome …
hyperinflammatory condition induced by infection with severe acute respiratory syndrome …
Downregulation of exhausted cytotoxic T cells in gene expression networks of multisystem inflammatory syndrome in children
Multisystem inflammatory syndrome in children (MIS-C) presents with fever, inflammation
and pathology of multiple organs in individuals under 21 years of age in the weeks following …
and pathology of multiple organs in individuals under 21 years of age in the weeks following …
SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial-derived cells and cardiomyocytes
Y Li, DM Renner, CE Comar… - Proceedings of the …, 2021 - National Acad Sciences
Coronaviruses are adept at evading host antiviral pathways induced by viral double-
stranded RNA, including interferon (IFN) signaling, oligoadenylate synthetase–ribonuclease …
stranded RNA, including interferon (IFN) signaling, oligoadenylate synthetase–ribonuclease …
Hemophagocytic lymphohistiocytosis gene variants in multisystem inflammatory syndrome in children
A Vagrecha, M Zhang, S Acharya, S Lozinsky, A Singer… - Biology, 2022 - mdpi.com
Simple Summary Children with a COVID-19 infection are at risk of developing a novel
syndrome called multisystem inflammatory syndrome in children (MIS-C). This disease state …
syndrome called multisystem inflammatory syndrome in children (MIS-C). This disease state …
Mechanisms underlying genetic susceptibility to multisystem inflammatory syndrome in children (MIS-C)
Background Multisystem inflammatory syndrome in children (MIS-C) is a pediatric
complication of severe acute respiratory syndrome coronavirus 2 infection that is …
complication of severe acute respiratory syndrome coronavirus 2 infection that is …
[HTML][HTML] Immune dysregulation and autoreactivity correlate with disease severity in SARS-CoV-2-associated multisystem inflammatory syndrome in children
A Ramaswamy, NN Brodsky, TS Sumida, M Comi… - Immunity, 2021 - cell.com
Multisystem inflammatory syndrome in children (MIS-C) is a life-threatening post-infectious
complication occurring unpredictably weeks after mild or asymptomatic SARS-CoV-2 …
complication occurring unpredictably weeks after mild or asymptomatic SARS-CoV-2 …
[HTML][HTML] Multisystem inflammatory syndrome in children occurred in one of four thousand children with severe acute respiratory syndrome coronavirus 2
M Holm, UB Hartling, LS Schmidt… - … (Oslo, Norway: 1992), 2021 - ncbi.nlm.nih.gov
Multisystem inflammatory syndrome in children (MIS-C) is a novel disease that is associated
with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). 1 Until now, only …
with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). 1 Until now, only …