Objective The standard opioid treatment for postoperative pain can be associated with
nausea, vomiting, and constipation. In addition, opioids often provide insufficient pain relief …

Introduction We present a randomized controlled trial to evaluate the value of the cyclo-
oxygenase-2 (COX-2) inhibitor, rofecoxib, as an adjuvant for pain management for patients …

Objective To compare 3 oral analgesic doses--valdecoxib 20 mg, valdecoxib 40 mg and
controlled-release diclofenac 75 mg--to placebo in the treatment of pain after inguinal …

IMPLICATIONS: Within the first 12 h after open herniorrhaphy in adults, a single dose of IV
parecoxib 40 mg compares favorably to propacetamol 2 g given twice. No difference was …

Introduction Inguinal and umbilical hernia repairs are among the most common surgical
procedures performed in the US. Optimal perioperative pain control regimens remain …

Background Inguinal hernia repair is a common procedure, and can be performed under
spinal anesthesia. Although adequate analgesia is crucial to postoperative recovery, the …

Aim: The purpose of this study was to investigate the analgesic effect of three different
regimens of analgesics administered to patients undergoing open inguinal hernia repair …

Objective: To evaluate the effects of two different doses of etoricoxib delivered
perioperatively compared with placebo and standard pain management on pain at rest, pain …

IMPLICATIONS: Rofecoxib (50 mg per os), given before and after surgery, was effective in
improving postoperative pain management, as well as the speed and quality of recovery …

Pain control is an important aspect in postoperative care. While opioids proved excellent
analgesia undesirable side effects such as respiratory depression, nausea and vomiting …