Effects of DNA mass on multiple displacement whole genome amplification and genotyping performance
AW Bergen, Y Qi, KA Haque, RA Welch, SJ Chanock - BMC biotechnology, 2005 - Springer
Background Whole genome amplification (WGA) promises to eliminate practical molecular
genetic analysis limitations associated with genomic DNA (gDNA) quantity. We evaluated …
genetic analysis limitations associated with genomic DNA (gDNA) quantity. We evaluated …
Evaluation of multiple displacement amplification in a 5 cM STR genome-wide scan
PA Dickson, GW Montgomery, A Henders… - Nucleic acids …, 2005 - academic.oup.com
Multiple displacement amplification (MDA) has emerged as a promising new method of
whole genome amplification (WGA) with the potential to generate virtually unlimited genome …
whole genome amplification (WGA) with the potential to generate virtually unlimited genome …
Comparison of yield and genotyping performance of multiple displacement amplification and OmniPlex™ whole genome amplified DNA generated from multiple DNA …
AW Bergen, KA Haque, Y Qi, MB Beerman… - Human …, 2005 - Wiley Online Library
The promise of whole genome amplification (WGA) is that genomic DNA (gDNA) quantity
will not limit molecular genetic analyses. Multiple displacement amplification (MDA) and the …
will not limit molecular genetic analyses. Multiple displacement amplification (MDA) and the …
Multiple displacement amplification to create a long‐lasting source of DNA for genetic studies
L Lovmar, AC Syvänen - Human mutation, 2006 - Wiley Online Library
In many situations there may not be sufficient DNA collected from patient or population
cohorts to meet the requirements of genome‐wide analysis of SNPs, genomic copy number …
cohorts to meet the requirements of genome‐wide analysis of SNPs, genomic copy number …
Genome‐wide single‐nucleotide polymorphism arrays demonstrate high fidelity of multiple displacement‐based whole‐genome amplification
MV Tzvetkov, C Becker, B Kulle, P Nürnberg… - …, 2005 - Wiley Online Library
Whole‐genome DNA amplification by multiple displacement (MD‐WGA) is a promising tool
to obtain sufficient DNA amounts from samples of limited quantity. Using …
to obtain sufficient DNA amounts from samples of limited quantity. Using …
Characterization of whole genome amplified (WGA) DNA for use in genotyping assay development
T Han, CW Chang, JC Kwekel, Y Chen, Y Ge… - BMC genomics, 2012 - Springer
Background Genotyping assays often require substantial amounts of DNA. To overcome the
problem of limiting amounts of available DNA, Whole Genome Amplification (WGA) methods …
problem of limiting amounts of available DNA, Whole Genome Amplification (WGA) methods …
Comparison of multiple displacement amplification (MDA) and multiple annealing and looping-based amplification cycles (MALBAC) in limited DNA sequencing …
X Zhou, Y Xu, L Zhu, Z Su, X Han, Z Zhang, Y Huang… - Micromachines, 2020 - mdpi.com
Whole genome amplification (WGA) is crucial for whole genome sequencing to investigate
complex genomic alteration at the single-cell or even single-molecule level. Multiple …
complex genomic alteration at the single-cell or even single-molecule level. Multiple …
Whole genome amplification and its impact on CGH array profiles
BA Talseth-Palmer, NA Bowden, A Hill, C Meldrum… - BMC research …, 2008 - Springer
Background Some array comparative genomic hybridisation (array CGH) platforms require a
minimum of micrograms of DNA for the generation of reliable and reproducible data. For …
minimum of micrograms of DNA for the generation of reliable and reproducible data. For …
Optimization and evaluation of single‐cell whole‐genome multiple displacement amplification
C Spits, C Le Caignec, M De Rycke… - Human …, 2006 - Wiley Online Library
The scarcity of genomic DNA can be a limiting factor in some fields of genetic research. One
of the methods developed to overcome this difficulty is whole genome amplification (WGA) …
of the methods developed to overcome this difficulty is whole genome amplification (WGA) …
Specific and complete human genome amplification with improved yield achieved by phi29 DNA polymerase and a novel primer at elevated temperature
Backgrounds Whole genome amplification (WGA) is a practical solution to eliminate
molecular analysis limitations associated with genomic DNA (gDNA) quantity. Different …
molecular analysis limitations associated with genomic DNA (gDNA) quantity. Different …
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