Due to a series of systemic and intracellular obstacles in nucleic acid (NA) therapy, including
fast degradation in blood, renal clearance, poor cellular uptake, and inefficient endosomal …

Nucleic acid‐based therapies are promising therapeutics for the treatment of several
systemic disorders, and they offer an exciting opportunity to address emerging biological …

Cascades of systemic and intracellular obstacles, including low stability in blood, little tumor
accumulation, weak tumor penetration, poor cellular uptake, inefficient endosomal escape …

Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several
issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A …

In the field of nanomedicine, ample attention has been paid to the development of
nanocarriers for the intracellular delivery of therapeutic cargo, such as nucleic acids for gene …

In the past few decades, substantial advancement has been made in nucleic acid (NA)-
based therapies. Promising treatments include mRNA, siRNA, miRNA, and anti-sense DNA …

Nucleic acid therapeutics can be used to control virtually every aspect of cell behavior and
therefore have significant potential to treat genetic disorders, infectious diseases, and …

There is growing need for a safe, efficient, specific and non-pathogenic means for delivery of
gene therapy materials. Nanomaterials for nucleic acid delivery offer an unprecedented …

With numerous recent advances, the field of therapeutic nucleic acid nanotechnology is now
poised for clinical translation supported by several examples of FDA-approved nucleic acid …

Delivery of genes, including plasmid DNAs, short interfering RNAs (siRNAs), and
messenger RNAs (mRNAs), using artificial non-viral nanotherapeutics is a promising …