The effect of maternal exposure to di‐(2‐ethylhexyl)‐phthalate on fetal cardiac development in mice

C Tang, Y Deng, H Duan, Y Zhang, Y Li… - Journal of Applied …, 2018 - Wiley Online Library
Accumulating evidence has suggested a link between maternal di‐(2‐ethylhexyl)‐phthalate
(DEHP) exposure and various developmental abnormalities. However, the evidence …

Maternal exposure to di-(2-ethylhexyl) phthalate disrupts placental growth and development in pregnant mice

T Zong, L Lai, J Hu, M Guo, M Li, L Zhang… - Journal of hazardous …, 2015 - Elsevier
Abstract Di-(2-ethylhexyl) phthalate (DEHP) is used as a plasticizer and widely dispersed in
the environment. DEHP exposure reduces embryo implantations, increases embryonic loss …

From the Cover: Teratogenic Effects of in Utero Exposure to Di-(2-Ethylhexyl)-Phthalate (DEHP) in B6:129S4 Mice

E Ungewitter, E Rotgers, T Bantukul… - Toxicological …, 2017 - academic.oup.com
Intrauterine exposure to phthalates is known to cause disorders of male reproductive
function including androgen insufficiency, decreased fertility, and germ cell defects in …

[HTML][HTML] Placental P-glycoprotein inhibition enhances susceptibility to Di-(2-ethylhexyl)-phthalate induced cardiac malformations in mice: A possibly promising target …

C Tang, C Luo, Y Hua, K Zhou, H Duan, F Ma, Y Zhang… - Plos one, 2019 - journals.plos.org
Backgrounds Reducing toxicants transplacental rates could contribute to the prevention of
congenital heart defects (CHDs). Placental P-glycoprotein (P-gp) plays a vital role in fetal …

Effect of di-(2-ethylhexyl) phthalate exposure on placental development in pregnant mice

L Zhang, TL Zhang, T Zong, YL Chen… - … Fang yi ke da xue xue …, 2016 - europepmc.org
Objective To investigate the effect of di-(2-ethylhexyl) phthalate (DEHP) exposure on the
growth and development of placenta, uterine natural killer (uNK) cell number and …

Di (2-ethylhexyl) phthalate exposure during prenatal development causes adverse transgenerational effects on female fertility in mice

S Rattan, E Brehm, L Gao, JA Flaws - Toxicological Sciences, 2018 - academic.oup.com
Abstract Di (2-ethylhexyl) phthalate (DEHP) is a ubiquitous environmental toxicant and
endocrine disrupting chemical, but little is known about its effects on female reproduction …

Di-2-ethylhexyl phthalate induces heart looping disorders during zebrafish development

Y Sun, F Yang, Y Liu, M Yu, F Wu… - … and Industrial Health, 2021 - journals.sagepub.com
Di-2-ethylhexyl phthalate (DEHP) is a type of plasticizer widely used in industry. It is well-
known for its toxic effects to endocrine and reproductive systems and has been detected in …

Evaluation of di (2‐ethylhexyl) phthalate‐induced embryotoxicity in rodent whole‐embryo culture

DK Hansen, TF Grafton - … and Environmental Health, Part A Current …, 1994 - Taylor & Francis
Di (2‐ethylhexyl) phthalate (DEHP) is a commonly used plasticizer. Human exposure has
been documented, and therefore it is important to investigate the toxic potential of this …

Comparative developmental toxicity evaluation of di-n-hexyl phthalate and dicyclohexyl phthalate in rats

MA Ahbab, C Güven, EA Koçkaya… - … and Industrial Health, 2017 - journals.sagepub.com
To investigate the effects of di-n-hexyl phthalate (DHP) and dicyclohexyl phthalate (DCHP)
on the development of fetus and placenta in utero, pregnant rats were exposed to DHP or …

Impact of di‐ethylhexylphthalate exposure on metabolic programming in P19 ECC‐derived cardiomyocytes

K Schaedlich, JS Schmidt, WY Kwong… - Journal of Applied …, 2015 - Wiley Online Library
Abstract Di (2‐ethylhexyl) phthalate (DEHP) is the most common plasticizer in plastic
devices of everyday use. It is a ubiquitous environmental contaminant and primarily known …