Understanding and mapping the human connectome is a long-standing endeavor of
neuroscience, yet the significant challenges associated with the large size of the human …

Human brain tissue models and organoids are vital for studying and modeling human
neurological disease. However, the high cost of long-term cultured organoids inhibits their …

Histology and immunohistochemistry are routine methods of analysis to visualize
microscopic anatomy and localize proteins within biological tissue. In neuroscience, as well …

Full article: Integrating Nanoscale Technologies with Cryogenics: A Step Towards Improved
Biopreservation Skip to Main Content Taylor and Francis Online homepage Taylor and Francis …

We describe here a new cryobiological and neurobiological technique, aldehyde-stabilized
cryopreservation (ASC), which demonstrates the relevance and utility of advanced …

Cryo-electron microscopy (cryo-EM) enables the study of protein complexes, cytoskeletal
elements, and organelles in three dimensions without the use of chemical fixation. Most cryo …

Demonstrated in this video are the techniques for flash freezing and sectioning embryonic
brain tissue from mouse. Useful tips for using the cryostat are given, including …

Cryopreservation is a well-established technique for long-term storage of viable cells and
tissues. However, in recent years, application of established cryobiological principles to the …

Cell cryopreservation improves reproducibility and enables flexibility in experimental design.
Although conventional freezing methodologies have been used to preserve primary …

Cryosurgery is a widely regarded minimally invasive surgery for treatment of various types of
cancers. It involves destruction of cancer cells within a limited spatial domain by exposing …