Development and challenges of antimicrobial peptides for therapeutic applications
More than 3000 antimicrobial peptides (AMPs) have been discovered, seven of which have
been approved by the US Food and Drug Administration (FDA). Now commercialized, these …
been approved by the US Food and Drug Administration (FDA). Now commercialized, these …
Will new generations of modified antimicrobial peptides improve their potential as pharmaceuticals?
NK Brogden, KA Brogden - International journal of antimicrobial agents, 2011 - Elsevier
The concept of antimicrobial peptides (AMPs) as potent pharmaceuticals is firmly
established in the literature, and most research articles on this topic conclude by stating that …
established in the literature, and most research articles on this topic conclude by stating that …
Antimicrobial peptides as therapeutic agents: Opportunities and challenges
M Mahlapuu, C Björn, J Ekblom - Critical reviews in biotechnology, 2020 - Taylor & Francis
The rapid development of microbial resistance to conventional antibiotics has accelerated
efforts to find anti-infectives with a novel mode-of-action, which are less prone to bacterial …
efforts to find anti-infectives with a novel mode-of-action, which are less prone to bacterial …
Discovery, optimization, and clinical application of natural antimicrobial peptides
Antimicrobial peptides (AMPs) are widespread in multicellular organisms. These structurally
diverse molecules are produced as the first line of defense against pathogens such as …
diverse molecules are produced as the first line of defense against pathogens such as …
The therapeutic applications of antimicrobial peptides (AMPs): a patent review
HK Kang, C Kim, CH Seo, Y Park - Journal of microbiology, 2017 - Springer
Antimicrobial peptides (AMPs) are small molecules with a broad spectrum of antibiotic
activities against bacteria, yeasts, fungi, and viruses and cytotoxic activity on cancer cells, in …
activities against bacteria, yeasts, fungi, and viruses and cytotoxic activity on cancer cells, in …
Antimicrobial peptides—Mechanisms of action, antimicrobial effects and clinical applications
The growing emergence of antimicrobial resistance represents a global problem that not
only influences healthcare systems but also has grave implications for political and …
only influences healthcare systems but also has grave implications for political and …
Characterization of antimicrobial peptides toward the development of novel antibiotics
W Aoki, M Ueda - Pharmaceuticals, 2013 - mdpi.com
Antimicrobial agents have eradicated many infectious diseases and significantly improved
our living environment. However, abuse of antimicrobial agents has accelerated the …
our living environment. However, abuse of antimicrobial agents has accelerated the …
Antimicrobial peptides (AMPs): A promising class of antimicrobial compounds
M Erdem Büyükkiraz, Z Kesmen - Journal of applied …, 2022 - academic.oup.com
Antimicrobial peptides (AMPs) are compounds, which have inhibitory activity against
microorganisms. In the last decades, AMPs have become powerful alternative agents that …
microorganisms. In the last decades, AMPs have become powerful alternative agents that …
Antimicrobial peptides: premises and promises
KVR Reddy, RD Yedery, C Aranha - International journal of antimicrobial …, 2004 - Elsevier
Antimicrobial peptides (AMPs) are an important component of the natural defences of most
living organisms against invading pathogens. These are relatively small (< 10kDa), cationic …
living organisms against invading pathogens. These are relatively small (< 10kDa), cationic …
Antimicrobial peptides: current status and therapeutic potential
AR Koczulla, R Bals - Drugs, 2003 - Springer
Antimicrobial peptides (AMPs) are effector molecules of the innate immune system. A variety
of AMPs have been isolated from species of all kingdoms and are classified based on their …
of AMPs have been isolated from species of all kingdoms and are classified based on their …
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