Single-cell sequencing identifies differentiation-related markers for molecular classification and recurrence prediction of PitNET

Q Zhang, B Yao, X Long, Z Chen, M He, Y Wu… - Cell Reports …, 2023 - cell.com
Pituitary neuroendocrine tumor (PitNET) is one of the most common intracranial tumors with
variable recurrence rate. Currently, the recurrence prediction is unsatisfying and can be …

Annotation of pituitary neuroendocrine tumors with genome-wide expression analysis

A Tebani, J Jotanovic, N Hekmati, Å Sivertsson… - Acta neuropathologica …, 2021 - Springer
Pituitary neuroendocrine tumors (PitNETs) are common, generally benign tumors with
complex clinical characteristics related to hormone hypersecretion and/or growing sellar …

Integrated proteogenomic characterization across major histological types of pituitary neuroendocrine tumors

F Zhang, Q Zhang, J Zhu, B Yao, C Ma, N Qiao, S He… - Cell Research, 2022 - nature.com
Pituitary neuroendocrine tumor (PitNET) is one of the most common intracranial tumors. Due
to its extensive tumor heterogeneity and the lack of high-quality tissues for biomarker …

Role of tumor microenvironment in pituitary neuroendocrine tumors: New approaches in classification, diagnosis and therapy

DA Tapoi, ML Popa, C Tanase, D Derewicz… - Cancers, 2023 - mdpi.com
Simple Summary Pituitary adenomas are highly prevalent intracranial neoplasms that can
be locally invasive in up to half of cases. Consequently, using the term “PitNETs”(pituitary …

Single-cell transcriptome and genome analyses of pituitary neuroendocrine tumors

Y Cui, C Li, Z Jiang, S Zhang, Q Li, X Liu… - Neuro …, 2021 - academic.oup.com
Abstract Background Pituitary neuroendocrine tumors (PitNETs) are the second most
common intracranial tumor. We lacked a comprehensive understanding of the pathogenesis …

Large scale molecular studies of pituitary neuroendocrine tumors: Novel markers, mechanisms and translational perspectives

R Peculis, H Niedra, V Rovite - Cancers, 2021 - mdpi.com
Simple Summary Pituitary neuroendocrine tumors are non-cancerous tumors of the pituitary
gland, that may overproduce hormones leading to serious health conditions or due to tumor …

Overview of the 2022 WHO classification of pituitary adenomas/pituitary neuroendocrine tumors: clinical practices, controversies, and perspectives

X Wan, J Chen, J Wang, Y Liu, K Shu, T Lei - Current Medical Science, 2022 - Springer
The latest edition of the WHO classification of the central nervous system was published in
2021. This review summarizes the major revisions to the classification of anterior pituitary …

Unveiling the identities of null cell tumours: epigenomics corroborate subtle histological cues in pituitary neuroendocrine tumour/adenoma classification

M Dottermusch, U Schüller, C Hagel… - Neuropathology and …, 2023 - Wiley Online Library
Abstract Aims Pituitary neuroendocrine tumour (PitNET)/adenoma classification is based on
cell lineage and requires immunopositivity for adenohypophysial hormones and/or …

Overview of the 2022 WHO classification of pituitary tumors

SL Asa, O Mete, A Perry, RY Osamura - Endocrine pathology, 2022 - Springer
This review summarizes the changes in the 5th Edition of the WHO Classification of
Endocrine and Neuroendocrine Tumors that relate to the pituitary gland. The new …

Pituitary neuroendocrine tumors with PIT1/SF1 co-expression show distinct clinicopathological and molecular features

M Dottermusch, A Ryba, FL Ricklefs, J Flitsch… - Acta …, 2024 - Springer
Pituitary neuroendocrine tumors (PitNETs) are classified according to cell lineage, which
requires immunohistochemistry for adenohypophyseal hormones and the transcription …