The formation of adipocytes during embryogenesis has been largely understudied.
However, preadipocytes appear to originate from multipotent mesenchymal stromal/stem …

The obesity epidemic has focused attention on adipose tissue and the development of fat
cells (ie adipocytes), which is known as adipogenesis. Peroxisome proliferator-activated …

Adipocyte differentiation is a highly controlled process that has been extensively studied for
the last 25 years. Two different kinds of in vitro experimental models, essential in …

Obesity and lipoatrophy are major risks for insulin resistance, non-insulin-dependent
diabetes and cardiovascular disease. In the past three decades, significant advances have …

Gregoire, Francine M., Cynthia M. Smas, and Hei Sook Sul. Understanding Adipocyte
Differentiation. Physiol. Rev. 78: 783–809, 1998.—The adipocyte plays a critical role in …

Adipocytes are the defining cell type of adipose tissue. Once considered a passive
participant in energy storage, adipose tissue is now recognized as a dynamic organ that …

Recent advances regarding the biology of adipose tissue have identified the adipocyte as
an important mediator in many physiologic and pathologic processes regarding energy …

Understanding adipogenesis, the process of adipocyte development, may provide new ways
to treat obesity and related metabolic diseases. Adipogenesis is controlled by coordinated …

The formation of adipocytes from precursor stem cells involves a complex and highly
orchestrated programme of gene expression. Our understanding of the basic network of …

Studies from the past several years have revealed that adipogenesis is controlled by an
interplay of transcription factors, including members of the CCAAT/enhancer binding protein …