How to turn up the heat on the cold immune microenvironment of metastatic prostate cancer

J Stultz, L Fong - Prostate cancer and prostatic diseases, 2021 - nature.com
Background Advanced prostate cancer remains one of the most common and deadly
cancers, despite advances in treatment options. Immunotherapy has provided little benefit to …

Prostate cancer immunotherapy—finally in from the cold?

KD Runcie, MC Dallos - Current oncology reports, 2021 - Springer
Abstract Purpose of Review Despite significant progress, patients with metastatic prostate
cancer continue to have poor prognosis. Immunotherapy has revolutionized cancer care for …

Immunotherapy in treatment of metastatic prostate cancer: An approach to circumvent immunosuppressive tumor microenvironment

BL Sun - The Prostate, 2021 - Wiley Online Library
Prostate cancer is the second most common cause of cancer‐related death in men in the
United States and the fifth worldwide. Most prostate cancer arises as an androgen …

Revisiting immunotherapy: a focus on prostate cancer

HR Cha, JH Lee, S Ponnazhagan - Cancer research, 2020 - AACR
Therapeutic interventions to harness the immune system against tumor cells have provided
mixed results in the past for several solid tumors and hematologic malignancies. However …

Immune infiltration and prostate cancer

A Strasner, M Karin - Frontiers in oncology, 2015 - frontiersin.org
It is becoming increasingly clear that inflammation influences prostate cancer (PCa)
development and that immune cells are among the primary drivers of this effect. This …

Immunotherapy of prostate cancer: facts and hopes

M Bilusic, RA Madan, JL Gulley - Clinical Cancer Research, 2017 - AACR
In the last few years, immunotherapy has become an important cancer treatment modality,
and although the principles of immunotherapy have evolved over many decades, the FDA …

Immunotherapy in prostate cancer

EK Fay, JN Graff - Cancers, 2020 - mdpi.com
Immunotherapy encompasses a wide range of therapies to engage the immune system to
target malignancies. In recent years, immunotherapy has made a major impact on treatment …

Past, current, and future of immunotherapies for prostate cancer

AN Boettcher, A Usman, A Morgans… - Frontiers in …, 2019 - frontiersin.org
Prostate cancer (PCa) is the most common cancer in men, and the second leading cause of
cancer related death in men in Western countries. The standard therapy for metastatic PCa …

Immunotherapy in prostate cancer: teaching an old dog new tricks

MC Comiskey, MC Dallos, CG Drake - Current oncology reports, 2018 - Springer
Immunotherapy is rapidly transforming cancer care across a range of tumor types. Although
Sipuleucel-T represented the first successful vaccine for the treatment of established cancer …

Is there a role for immunotherapy in prostate cancer?

A Rizzo, V Mollica, A Cimadamore, M Santoni… - Cells, 2020 - mdpi.com
In the last decade, immunotherapy has revolutionized the treatment landscape of several
hematological and solid malignancies, reporting unprecedented response rates …