Efecto de las lipoproteínas de alta densidad sobre la microvasculatura cerebral en la enfermedad del alzhéimer.

C Iribar Zubiaur - 2023 - idus.us.es
Las lipoproteínas de alta densidad (HDL) juegan un papel importante en la patología de la
enfermedad de Alzheimer (EA) y la demencia vascular, ya que tienen efectos tanto …

The small HDL particle hypothesis of Alzheimer's disease

AE Martinez, G Weissberger, Z Kuklenyik… - Alzheimer's & …, 2023 - Wiley Online Library
We propose the hypothesis that small high‐density lipoprotein (HDL) particles reduce the
risk of Alzheimer's disease (AD) by virtue of their capacity to exchange lipids, affecting …

Science Center at Tyler, United States Juno Van Valkenburgh1†, Cristiana Meuret2†, Ashley E. Martinez2, Vibha Kodancha2, Victoria Solomon2, Kai Chen1* and …

C Wellington, GA Francis, CO Mendivil… - … and Transport in …, 2021 - books.google.com
High-density lipoproteins (HDLs) are complex, heterogenous lipoprotein particles,
consisting of a large family of apolipoproteins, formed in subspecies of distinct shapes …

High‐density lipoprotein particle size distribution among patients with Alzheimer's disease, mild cognitive impairment, and age‐matched controls

JJ Zheng, BV Hong, J Agus, X Tang… - Alzheimer's & …, 2023 - Wiley Online Library
Background High‐density lipoproteins (HDL) are protective against several chronic
diseases, including Alzheimer's disease (AD). The size distribution of HDL particles is one of …

Low levels of high density lipoprotein increase the severity of cerebral white matter changes: implications for prevention and treatment of cerebrovascular diseases

M Crisby, L Bronge, LO Wahlund - Current Alzheimer Research, 2010 - ingentaconnect.com
Background and Purpuse: Cerebral White matter changes (WMC) are a frequent finding on
CT and MRI scans of elderly individuals, particularly in those with vascular risk factors …

HDL from an Alzheimer's disease perspective

EB Button, J Robert, TM Caffrey, J Fan… - Current opinion in …, 2019 - journals.lww.com
Evidence from human studies, animal models, and bioengineered arteries supports the
hypothesis that HDL protects against cerebrovascular dysfunction in Alzheimer's disease …

High density lipoprotein cholesterol and apolipoprotein AI are associated with greater cerebral perfusion in multiple sclerosis

D Jakimovski, R Zivadinov, MG Dwyer… - Journal of the …, 2020 - Elsevier
Background The pathophysiological mechanisms underlying the associations of multiple
sclerosis (MS) neurodegeneration serum cholesterol profiles is currently unknown. Objective …

Exposure of HDL to Amyloid Beta alters its interaction with brain endothelial cells

E Ermani - 2023 - zora.uzh.ch
Alzheimer's disease (AD) is a devastating neurodegenerative pathology and the leading
cause of dementia. The incidence of dementia is drastically increasing over the years. AD is …

Ischemic stroke patients with carotid atherosclerosis show dysfunctional high-density lipoprotein particles

N Puig, A Solé, A Aguilera-Simón… - …, 2023 - atherosclerosis-journal.com
Methods: Plasma was obtained from the healthy controls (n= 27) and from the ischemic
stroke patients with carotid atherosclerosis (n= 64) at 7 days (7d) and 1 year (1y) from the …

Understanding the exchange of systemic HDL particles into the brain and vascular cells has diagnostic and therapeutic implications for neurodegenerative diseases

J Van Valkenburgh, C Meuret, AE Martinez… - Frontiers in …, 2021 - frontiersin.org
High-density lipoproteins (HDLs) are complex, heterogenous lipoprotein particles,
consisting of a large family of apolipoproteins, formed in subspecies of distinct shapes …