The present work revealed a novel one-pot synthesis of 2-oxo-1, 2, 3, 4-
tetrahydropyrimidines. It involved the use of methyl arenes as a surrogate of aldehydes, in …

The chemistry of 2-oxo-1, 2, 3, 4-tetrahydropyrimidines began to develop toward the end of
1893 year, when the first representatives of this class compounds were reported by P …

An efficient of one-pot oxidative access to 3, 4-dihydropyrimidin-2-(1H)-ones directly from
aromatic alcohols under mild conditions is reported. The protocol involves 1 …

Abstract The Biginelli Reaction is a cyclo-condensation process that is one-pot acid-
catalyzed and produces functionalized DHPMs by combining urea, β-keto ester, and …

An expeditious synthesis of novel 3, 4-dihydropyrimidin-2 (1H)-one derivatives has been
developed using a multi-component reaction involving the in situ generation of non …

Multicomponent reactions are considered to be of increasing importance as time progresses
due to the economic and environmental advantages such strategies entail. The three …

Abstract Biginelli compounds 3, 4-dihydropyrimidine-2-(1 H)-ones are synthesized in high
yields via eco-friendly simple reaction procedure using Lactic acid: organocatalyst. The new …

A mild and efficient catalytic method has been developed to synthesize 3, 4-
dihydropyrimidinones in high yield by one-pot three component Biginelli condensation in the …

Multicomponent reactions (MCRs) are chemical reactions in which three or more
compounds react to form a single product. In the present work Biginelli reaction was …

The Biginelli Reaction is a one-pot acid catalysed cyclocondensation of β-keto ester, urea
and aromatic aldehyde which leads to the synthesis of functionalised 3, 4-dihydro-2 (H) …