Standardization can accelerate the adoption of pharmacogenomics: current status and the path forward
KE Caudle, NJ Keeling, TE Klein… - …, 2018 - Taylor & Francis
Successfully implementing pharmacogenomics into routine clinical practice requires an
efficient process to order genetic tests and report the results to clinicians and patients. Lack …
efficient process to order genetic tests and report the results to clinicians and patients. Lack …
[HTML][HTML] Standardizing terms for clinical pharmacogenetic test results: consensus terms from the Clinical Pharmacogenetics Implementation Consortium (CPIC)
KE Caudle, HM Dunnenberger, RR Freimuth… - Genetics in …, 2017 - Elsevier
Introduction Reporting and sharing pharmacogenetic test results across clinical laboratories
and electronic health records is a crucial step toward the implementation of clinical …
and electronic health records is a crucial step toward the implementation of clinical …
Challenges and opportunities in implementing pharmacogenetic testing in clinical settings
The clinical implementation of pharmacogenetic biomarkers continues to grow as new
genetic variants associated with drug outcomes are discovered and validated. The number …
genetic variants associated with drug outcomes are discovered and validated. The number …
CPIC: clinical pharmacogenetics implementation consortium of the pharmacogenomics research network
MV Relling, TE Klein - Clinical Pharmacology & Therapeutics, 2011 - Wiley Online Library
The slow rate at which pharmacogenetic tests are being adopted in clinical practice is partly
due to the lack of specific guidelines on how to adjust medications on the basis of the …
due to the lack of specific guidelines on how to adjust medications on the basis of the …
[HTML][HTML] Clinical pharmacogenomic testing and reporting: A technical standard of the American College of Medical Genetics and Genomics (ACMG)
Pharmacogenomic testing interrogates germline sequence variants implicated in
interindividual drug response variability to infer a drug response phenotype and to guide …
interindividual drug response variability to infer a drug response phenotype and to guide …
Pharmacogenomics implementation: considerations for selecting a reference laboratory
TT Vo, GC Bell, A Owusu Obeng… - … : The Journal of …, 2017 - Wiley Online Library
One of the initial steps for implementing pharmacogenomics into routine patient care is
selecting an appropriate clinical laboratory to perform the testing. With the rapid advances in …
selecting an appropriate clinical laboratory to perform the testing. With the rapid advances in …
Pharmacogenetic tests: the need for a level playing field
M Pirmohamed, DA Hughes - Nature reviews Drug discovery, 2013 - nature.com
The delivery of more personalized medicinecould be accelerated by addressing the
substantial differences in the level of evidence required for the inclusion of pharmacogenetic …
substantial differences in the level of evidence required for the inclusion of pharmacogenetic …
Clinical application of pharmacogenetics: focusing on practical issues
MT Chang, JJ McCarthy, J Shin - Pharmacogenomics, 2015 - Taylor & Francis
Recent large-scale genetic-based studies have transformed the field of pharmacogenetics to
identify, characterize and leverage genetic information to inform patient care. Genetic testing …
identify, characterize and leverage genetic information to inform patient care. Genetic testing …
[HTML][HTML] Incorporation of pharmacogenomics into routine clinical practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline development …
Abstract The Clinical Pharmacogenetics Implementation Consortium (CPIC) publishes
genotype-based drug guidelines to help clinicians understand how available genetic test …
genotype-based drug guidelines to help clinicians understand how available genetic test …
Evidence and resources to implement pharmacogenetic knowledge for precision medicine
KE Caudle, RS Gammal, M Whirl-Carrillo… - American Journal of …, 2016 - academic.oup.com
Purpose The current state of pharmacogenetic data curation and dissemination is described,
and evidence-based resources for applying pharmacogenetic data in clinical practice are …
and evidence-based resources for applying pharmacogenetic data in clinical practice are …