Introduction Longitudinal testing is necessary to accurately measure cognitive change.
However, repeated testing is susceptible to practice effects, which may obscure true …

Background: Practice effects have been widely reported in healthy older adults, but these
improvements due to repeat exposure to test materials have been more equivocal in …

Objective Practice effects on cognitive tests have been shown to further characterize patients
with amnestic mild cognitive impairment (aMCI) and may provide predictive information …

Objective: Screening of normal older persons for progressive memory decline is a
worthwhile strategy in the pursuit of the earliest possible stages of pre-clinical Alzheimer's …

Background On average, health worsens with age, but many people have periods of
improvement. A stochastic model provides an excellent description of how such changes …

Objective To determine if the addition of delayed recall (DR) assessment adds sensitivity to
the cognitive subscale of the Alzheimer Disease Assessment Scale (ADAS-cog) in clinical …

Backgound Identifying mild cognitive impairment (MCI) in midlife could improve early
identification of Alzheimer's disease (AD). Also, AD is highly heritable, but the heritability of …

Introduction This study examined whether, among subjects with mild cognitive impairment
(MCI), women progressed at faster rates than men. Methods We examine longitudinal rates …

BACKGROUND: The Mini-Mental State Examination continues to be used frequently to
screen for cognitive impairment in older adults, but it remains unclear how to interpret …

The objective of this study was to examine practice effects and longitudinal cognitive change
in a population-based cohort classified as clinically normal at their initial evaluation. We …