SRPassing co-translational targeting: the role of the signal recognition particle in protein targeting and mRNA protection
MK Kellogg, SC Miller, EB Tikhonova… - International journal of …, 2021 - mdpi.com
Signal recognition particle (SRP) is an RNA and protein complex that exists in all domains of
life. It consists of one protein and one noncoding RNA in some bacteria. It is more complex …
life. It consists of one protein and one noncoding RNA in some bacteria. It is more complex …
[PDF][PDF] Molecular mechanism of cargo recognition and handover by the mammalian signal recognition particle
A Jomaa, S Eitzinger, Z Zhu, S Chandrasekar… - Cell reports, 2021 - cell.com
Co-translational protein targeting to membranes by the signal recognition particle (SRP) is a
universally conserved pathway from bacteria to humans. In mammals, SRP and its receptor …
universally conserved pathway from bacteria to humans. In mammals, SRP and its receptor …
Structural insights into the signal recognition particle
▪ Abstract The signal recognition particle (SRP) directs integral membrane and secretory
proteins to the cellular protein translocation machinery during translation. The SRP is an …
proteins to the cellular protein translocation machinery during translation. The SRP is an …
Interaction of signal-recognition particle 54 GTPase domain and signal-recognition particle RNA in the free signal-recognition particle
T Hainzl, S Huang… - Proceedings of the …, 2007 - National Acad Sciences
The signal-recognition particle (SRP) is a ubiquitous protein–RNA complex that targets
proteins to cellular membranes for insertion or secretion. A key player in SRP-mediated …
proteins to cellular membranes for insertion or secretion. A key player in SRP-mediated …
The signal recognition particle (SRP) RNA links conformational changes in the SRP to protein targeting
N Bradshaw, P Walter - Molecular biology of the cell, 2007 - Am Soc Cell Biol
The RNA component of the signal recognition particle (SRP) is universally required for
cotranslational protein targeting. Biochemical studies have shown that SRP RNA …
cotranslational protein targeting. Biochemical studies have shown that SRP RNA …
Signal recognition particle-depencent protein targeting, universal to all kingdoms of life
HG Koch, M Moser, M Müller - Reviews of physiology, biochemistry and …, 2002 - Springer
The signal recognition particle (SRP) and its membrane-bound receptor represent a
ubiquitous protein-targeting device utilized by organisms as different as bacteria and …
ubiquitous protein-targeting device utilized by organisms as different as bacteria and …
Binding Sites of the 9- and 14-Kilodalton Heterodimeric Protein Subunit of the Signal Recognition Particle (SRP) Are Contained Exclusively in the Alu Domain of SRP …
K Strub, J Moss, P Walter - Molecular and Cellular Biology, 1991 - Taylor & Francis
The mammalian signal recognition particle (SRP) is a small cytoplasmic ribonucleoprotein
required for the cotranslational targeting of secretory proteins to the endoplasmic reticulum …
required for the cotranslational targeting of secretory proteins to the endoplasmic reticulum …
[HTML][HTML] Structure, function and evolution of the signal recognition particle
K Nagai, C Oubridge, A Kuglstatter, E Menichelli… - The EMBO …, 2003 - embopress.org
The signal recognition particle (SRP) is a ribonucleoprotein particle essential for the
targeting of signal peptide-bearing proteins to the prokaryotic plasma membrane or the …
targeting of signal peptide-bearing proteins to the prokaryotic plasma membrane or the …
S-domain assembly of the signal recognition particle
AE Sauer-Eriksson, T Hainzl - Current opinion in structural biology, 2003 - Elsevier
The signal recognition particle (SRP) is a phylogenetically conserved ribonucleoprotein that
associates with ribosomes to mediate the targeting of membrane and secretory proteins to …
associates with ribosomes to mediate the targeting of membrane and secretory proteins to …
Identification and comparative analysis of components from the signal recognition particle in protozoa and fungi
MA Rosenblad, C Zwieb, T Samuelsson - BMC genomics, 2004 - Springer
Background The signal recognition particle (SRP) is a ribonucleoprotein complex
responsible for targeting proteins to the ER membrane. The SRP of metazoans is well …
responsible for targeting proteins to the ER membrane. The SRP of metazoans is well …