Purpose To identify specific dry eye disease (DED) tear biomarker (s) using tear proteomic
analysis, clinical parameters, and their correlations before and after DED treatment. Methods …

Purpose: To compare the changes in human tear proteome and clinical effects following
topical cyclosporine A (CsA) 0.05% or diquafosol tetrasodium (DQS) 3% treatment of dry eye …

Purpose To evaluate the effect of 0.1%-fluorometholone (FML) on tear inflammatory
molecule levels after 22-days treatment in dry eye disease (DED) patients exposed to an …

Dry eye disease (DED) is a commonly occurring, multifactorial disease characterized by
reduced tear film stability and hyperosmolarity at the ocular surface, leading to discomfort …

Dry eye is a common clinical condition diagnosed by cumulative evidence of symptoms and
signs. Many new treatments in dry eye are either expensive, invasive, have potential for side …

Methods.: In this prospective study, based on the ocular surface disease index (OSDI) and
corneal staining (CS), 95 DED patients (OSDI≥ 13) with increasing CS were enrolled into 3 …

Publication of the DEWS report in 2007 established the state of the science of dry eye
disease (DED). Since that time, new evidence suggests that a rethinking of traditional …

Purpose.: Previous studies demonstrated alterations in the tear proteome of dry eye patients.
The aim of the present study was to analyze tear protein patterns of dry eye patients …

The diagnosis of dry eye disease (the early stages in particular) is important, but difficult, due
to the lack of gold standards and poor correlation between tear biochemical changes and …

In recent years, there has been increasing scientific interest in the use of tear film biomarkers
in the diagnosis and management of dry eye disease (DED), owing to their potential …