Sympathetic hyperactivity plays an important and distinct role in hypertension associated
with chronic renal failure (CRF). Renal ischemia, elevated angiotensin II, and suppressed …

There is clear evidence that chronic kidney disease (CKD) is often characterized by the
presence of sympathetic hyperactivity. Importantly, data are accumulating that this …

Objective To review the current literature on sympathetic mediation of hypertension in
chronic renal failure. Background Hypertension is present in the vast majority of patients with …

The potential involvement of sympathetic overactivity has been neglected in this population
despite accumulating experimental and clinical evidence suggesting a crucial role of …

Much evidence indicates increased sympathetic nervous activity (SNA) in renal disease.
Renal ischemia is probably a primary event leading to increased SNA. Increased SNA often …

There is a dramatic increase in patients with end-stage re-nal failure due to diabetic
nephropathy, chronic glomerulonephritis and uncontrolled hypertension all over the world …

Sympathetic hyperactivity in chronic kidney disease: Pathogenesis, clinical relevance, and
treatment. Cardiovascular morbidity and mortality importantly influence live expectancy of …

Fig. 1. Synopsis of pathophysiological events leading to sympathetic overactivity in chronic
renal failure. For detailed explanation see text. to be yes! Ligtenberg and colleagues [7] …

Background. Hypertension is a frequent complication of chronic renal failure, but its causes
are not fully understood. There is indirect evidence that increased activity of the sympathetic …

Background Inhibition of angiotensin-converting enzyme (ACE) reduces the risk of
cardiovascular problems in patients with chronic renal failure. This effect may be due in part …