Video game training enhances cognitive control in older adults

JA Anguera, J Boccanfuso, JL Rintoul, O Al-Hashimi… - Nature, 2013 - nature.com
Cognitive control is defined by a set of neural processes that allow us to interact with our
complex environment in a goal-directed manner. Humans regularly challenge these control …

[HTML][HTML] Functional alterations of the prefrontal circuit underlying cognitive aging in mice

HR Chong, Y Ranjbar-Slamloo, MZH Ho… - Nature …, 2023 - nature.com
Executive function is susceptible to aging. How aging impacts the circuit-level computations
underlying executive function remains unclear. Using calcium imaging and optogenetic …

Cognitive control persistently enhances hippocampal information processing

A Chung, C Jou, A Grau-Perales, ERJ Levy, D Dvorak… - Nature, 2021 - nature.com
Could learning that uses cognitive control to judiciously use relevant information while
ignoring distractions generally improve brain function, beyond forming explicit memories …

Memory failure predicted by attention lapsing and media multitasking

KP Madore, AM Khazenzon, CW Backes, J Jiang… - Nature, 2020 - nature.com
With the explosion of digital media and technologies, scholars, educators and the public
have become increasingly vocal about the role that an 'attention economy'has in our lives …

Reset of hippocampal–prefrontal circuitry facilitates learning

AJ Park, AZ Harris, KM Martyniuk, CY Chang, AI Abbas… - Nature, 2021 - nature.com
The ability to rapidly adapt to novel situations is essential for survival, and this flexibility is
impaired in many neuropsychiatric disorders. Thus, understanding whether and how novelty …

Shared mechanisms underlie the control of working memory and attention

MF Panichello, TJ Buschman - Nature, 2021 - nature.com
Cognitive control guides behaviour by controlling what, when, and how information is
represented in the brain. For example, attention controls sensory processing; top-down …

Projections from neocortex mediate top-down control of memory retrieval

P Rajasethupathy, S Sankaran, JH Marshel, CK Kim… - Nature, 2015 - nature.com
Top-down prefrontal cortex inputs to the hippocampus have been hypothesized to be
important in memory consolidation, retrieval, and the pathophysiology of major psychiatric …

Thalamic projections sustain prefrontal activity during working memory maintenance

SS Bolkan, JM Stujenske, S Parnaudeau… - Nature …, 2017 - nature.com
The mediodorsal thalamus (MD) shares reciprocal connectivity with the prefrontal cortex
(PFC), and decreased MD–PFC connectivity is observed in schizophrenia patients. Patients …

Neuronal basis of age-related working memory decline

M Wang, NJ Gamo, Y Yang, LE Jin, XJ Wang… - Nature, 2011 - nature.com
Many of the cognitive deficits of normal ageing (forgetfulness, distractibility, inflexibility and
impaired executive functions) involve prefrontal cortex (PFC) dysfunction,,,. The PFC guides …

Human dorsal anterior cingulate cortex neurons mediate ongoing behavioural adaptation

SA Sheth, MK Mian, SR Patel, WF Asaad, ZM Williams… - Nature, 2012 - nature.com
The ability to optimize behavioural performance when confronted with continuously evolving
environmental demands is a key element of human cognition. The dorsal anterior cingulate …