[HTML][HTML] The interplay between autophagy and ferroptosis presents a novel conceptual therapeutic framework for neuroendocrine prostate cancer

Y Wang, N Wu, J Li, J Liang, D Zhou, Q Cao, X Li… - Pharmacological …, 2024 - Elsevier
In American men, the incidence of prostate cancer (PC) is the highest among all types of
cancer, making it the second leading cause of mortality associated with cancer. For …

Unlocking ferroptosis in prostate cancer—the road to novel therapies and imaging markers

PHA Cao, A Dominic, FE Lujan, S Senthilkumar… - Nature Reviews …, 2024 - nature.com
Ferroptosis is a distinct form of regulated cell death that is predominantly driven by the build-
up of intracellular iron and lipid peroxides. Ferroptosis suppression is widely accepted to …

[HTML][HTML] Molecular mechanisms of ferroptosis and its role in prostate cancer therapy

S Wang, W Wei, N Ma, Y Qu, Q Liu - Critical reviews in oncology …, 2022 - Elsevier
Prostate cancer (PCa) is a highly prevalent disease that affects men's health worldwide and
is the second most common malignancy in males. Ferroptosis is a novel form of …

Ferroptosis landscape in prostate cancer from molecular and metabolic perspective

J Liang, Y Liao, P Wang, K Yang, Y Wang… - Cell Death …, 2023 - nature.com
Prostate cancer is a major disease that threatens men's health. Its rapid progression, easy
metastasis, and late castration resistance have brought obstacles to treatment. It is …

Roles of ferroptosis in urologic malignancies

S Zhao, P Li, W Wu, Q Wang, B Qian, X Li… - Cancer cell …, 2021 - Springer
Ferroptosis, an iron-dependent form of non-apoptotic cell death, is believed to strongly
contribute to the pathogenesis of multiple cancers. Recently, the positive association …

TFAP2C-mediated lncRNA PCAT1 inhibits ferroptosis in docetaxel-resistant prostate cancer through c-Myc/miR-25-3p/SLC7A11 signaling

X Jiang, S Guo, M Xu, B Ma, R Liu, Y Xu… - Frontiers in …, 2022 - frontiersin.org
Recent evidence has shown that the induction of ferroptosis is a new therapeutic strategy for
advanced prostate cancer (PCa) when used as a monotherapy or in combination with …

Cancer associated fibroblast secreted miR-432-5p targets CHAC1 to inhibit ferroptosis and promote acquired chemoresistance in prostate cancer

J Zhao, J Shen, L Mao, T Yang, J Liu, S Hongbin - Oncogene, 2024 - nature.com
Prostate cancer (PCa) ranks as the sixth most serious male malignant disease globally.
While docetaxel (DTX) chemotherapy is the standard treatment for advanced PCa patients …

Identifying a ferroptosis-related gene signature for predicting biochemical recurrence of prostate cancer

Z Lv, J Wang, X Wang, M Mo, G Tang, H Xu… - Frontiers in Cell and …, 2021 - frontiersin.org
Ferroptosis induced by lipid peroxidation is closely related to cancer biology. Prostate
cancer (PCa) is not only a malignant tumor but also a lipid metabolic disease. Previous …

Targeting tyrosine kinases and autophagy in prostate cancer

HJ Kung - Hormones and Cancer, 2011 - Springer
Tyrosine kinases play significant roles in tumor progression and therapy resistance.
Inhibitors of tyrosine kinases are on the forefront of targeted therapy. For prostate cancer …

[PDF][PDF] Prostate cancer cells at a therapeutic gunpoint of the autophagy process

F Gabriele, C Martinelli… - J. Cancer Metastasis …, 2018 - pdfs.semanticscholar.org
In a normal prostate, the process of controling cell death is essential to maintain tissue
homeostasis and its inhibition may lead to the development of cancer. Androgen receptor …