Background & Aims The advent of direct-acting antivirals (DAAs) has led to ambitious targets
for hepatitis C virus (HCV) elimination. However, in the context of alcohol use disorder the …

Background & Aims Population-level evidence for the impact of direct-acting antiviral (DAA)
therapy on hepatitis C virus (HCV)-related disease burden is lacking. We aimed to evaluate …

Liver cirrhosis and other chronic liver diseases are usually compartmentalized into separate
categories based on etiology (eg, due to alcohol, virus infection, etc.), but it is important to …

A substantial baseline risk of liver cirrhosis exists for patients with chronic hepatitis C virus
(HCV) infection. However, the extent to which this could be driven by heavy alcohol use is …

Background & Aims Hepatitis C virus (HCV) patients are at risk of alcohol use disorders
(AUDs). We measured the contribution of AUDs on the burden of chronic HCV infection in …

Alcohol use can cause hepatic necroinflammation and worsening portal hypertension in
patients with cirrhosis. We aimed to evaluate the associations between degree of alcohol …

Background & Aims Despite a marked reduction in new cases of cirrhosis caused by HCV
infection, over 500,000 new cirrhosis cases in this category were estimated globally in 2019 …

Background Cirrhosis is a heterogeneous clinical condition that includes patients at wide-
ranging stages of severity. The role of the underlying liver disease on patient prognosis …

Background & Aims Whether alcohol intake increases the risk of complications in patients
with HCV-related cirrhosis remains unclear. The aim of this study was to determine the …

Alcohol consumption and hepatitis C virus (HCV) infection have a synergic hepatotoxic
effect, and the coexistence of these factors increases the risk of advanced liver disease. The …