[PDF][PDF] 3-nitropropionic Acid 투여후마우스선조체에서Apurinic/Apyrimidinic Endonuclease 의발현과신경세포고사

조경주, 이두재, 이병인, 김경환 - 2005 - core.ac.uk
Background: 3-Nitroporpionic acid (3-NP) is an irreversible inhibitor of succinate
dehydrogenase in mitochondria and can induce apoptosis-like cell death in the striatum. It …

Expression of Apurinic/apyrimidinic Endonuclease and Neuronal Apoptosis in the Striatum after Treatment of 3-Nitropropionic Acid in Mice

KJ CHO, DJ LEE, BI LEE… - Journal of the Korean …, 2005 - pesquisa.bvsalud.org
BACKGROUND: 3-Nitroporpionic acid (3-NP) is an irreVersible inhibitor of succinate
dehydrogenase in mitochondria and can induce apoptosis-like cell death in the striatum. It …

Reduction of apurinic/apyrimidinic endonuclease expression after transient global cerebral ischemia in rats: implication of the failure of DNA repair in neuronal …

M Kawase, M Fujimura, Y Morita-Fujimura, PH Chan - Stroke, 1999 - Am Heart Assoc
Background and Purpose—To clarify the relationship between apurinic/apyrimidinic
endonuclease (APE/Ref-1), a multifunctional protein in the DNA base excision repair …

The adenoviral vector-mediated increase in apurinic/apyrimidinic endonuclease inhibits the induction of neuronal cell death after transient ischemic stroke in mice

HW Kim, KJ Cho, SC Park, HJ Kim, GW Kim - Brain research, 2009 - Elsevier
Despite the correlation between changes in the levels of apurinic/apyrimidinic
endonuclease and ischemic neuronal damage, no studies have addressed the question of …

Early decrease of apurinic/apyrimidinic endonuclease expression after transient focal cerebral ischemia in mice

M Fujimura, Y Morita-Fujimura… - Journal of Cerebral …, 1999 - journals.sagepub.com
The authors examined the protein expression of apurinic/apyrimidinic endonuclease
(APE/Ref-1), a multifunctional protein in the DNA base excision repair pathway, before and …

Yeast apurinic/apyrimidinic endonuclease Apn1 protects mammalian neuronal cell line from oxidative stress

R Ho, LI Rachek, Y Xu, MR Kelley… - Journal of …, 2007 - Wiley Online Library
Reactive oxygen species (ROS) have been implicated as one of the agents responsible for
many neurodegenerative diseases. A critical target for ROS is DNA. Most oxidative stress …

[PDF][PDF] Prokaryotic expression and characterization of human AP DNA endonuclease

SH Oh, DW Song, MY Lee - Yonsei Medical Journal, 1999 - synapse.koreamed.org
The expression of major human apurinic/apyrimidinic DNA endonuclease (APEX) from its
cDNA in E. coli (DH5 alpha) was attempted in order to obtain a biologically active …

Influence of apurinic/apyrimidinic endonuclease on repair of rat brain regions distant from the focal cerebral ischemia site

Q Huang, Y Shao, J Feng, L LI… - Chinese Journal of …, 2014 - pesquisa.bvsalud.org
Objective To investigate changes in the expression of apurinic/apyrimidinic endonuclease
(APE) and the oxidative DNA damage marker 8 OHdG in distant hippocampus regions of the …

Rapid Loss of Apurinic/Apyrimidinic Endonuclease and Subsequent Apoptosis in Kainate-Induced Seizure Model

HY SHIN, DJ LEE, KJ CHO, MA KIM… - Journal of Korean …, 2004 - pesquisa.bvsalud.org
PURPOSE: The DNA repair enzyme, apurinic/apyrimidinic endonuclease (APE) plays a role
in base excision repair pathway involved in repairing apurinic/apyrimidinic (AP) site after …

[引用][C] 3-nitropropionic Acid 투여후마우스선조체에서Apurinic/Apyrimidinic Endonuclease 의발현과신경세포고사

KJ Cho