BRAF-activated WT1 contributes to cancer growth and regulates autophagy and apoptosis in papillary thyroid carcinoma
X Chen, S Lin, Y Lin, S Wu, M Zhuo, A Zhang… - Journal of translational …, 2022 - Springer
Background Papillary thyroid carcinoma (PTC) is one of most prevalent malignant endocrine
neoplasms, and it is associated with a high frequency of BRAF gene mutations, which lead …
neoplasms, and it is associated with a high frequency of BRAF gene mutations, which lead …
[HTML][HTML] Epigenetically upregulated WIPF1 plays a major role in BRAF V600E-promoted papillary thyroid cancer aggressiveness
Abstract How the BRAF V600E mutation promotes the pathogenesis and aggressiveness of
papillary thyroid cancer (PTC) is not completely understood. Here we explored a novel …
papillary thyroid cancer (PTC) is not completely understood. Here we explored a novel …
STRA6 regulates tumor immune microenvironment and is a prognostic marker in BRAF-mutant papillary thyroid carcinoma
W He, Y Sun, J Ge, X Wang, B Lin, S Yu, Y Li… - Frontiers in …, 2023 - frontiersin.org
Background BRAF mutation is one of the most common genetic alterations contributing to
the initiation and progression of papillary thyroid carcinoma (PTC). However, the prognostic …
the initiation and progression of papillary thyroid carcinoma (PTC). However, the prognostic …
[HTML][HTML] Aberrant expression of BUB1B contributes to the progression of thyroid carcinoma and predicts poor outcomes for patients
H Yan, C Xiang - Journal of Cancer, 2022 - ncbi.nlm.nih.gov
Objective: This study aimed to clarify the function and potential mechanism of BUB1B in
THCA. Methods: Expression of BUB1B in THCA was firstly determined, and its important …
THCA. Methods: Expression of BUB1B in THCA was firstly determined, and its important …
High Expression of WWP1 Associates with Tumor Progression in Papillary Thyroid Cancer
X Wang, Y Bi, X Liu, L Liu, M Hao, M Tian… - Cancer Biotherapy & …, 2022 - liebertpub.com
Background: WWP1 (WW domain-containing E3 ubiquitin protein ligase 1) is increased in
several kinds of carcinomas, but the influence of WWP1 in papillary thyroid cancer (PTC) is …
several kinds of carcinomas, but the influence of WWP1 in papillary thyroid cancer (PTC) is …
Key candidate genes associated with BRAFV600E in papillary thyroid carcinoma on microarray analysis
X Yu, P Zhong, Y Han, Q Huang… - Journal of Cellular …, 2019 - Wiley Online Library
The mechanisms of B‐type Raf kinase (BRAF) V600E mutation in papillary thyroid cancer
(PTC) remain to be elucidated. With the aim to investigate the key candidate genes …
(PTC) remain to be elucidated. With the aim to investigate the key candidate genes …
β-Catenin Attenuation Inhibits Tumor Growth and Promotes Differentiation in a BRAFV600E-Driven Thyroid Cancer Animal Model
M Zou, HA BinEssa, YH Al-Malki, S Al-Yahya… - Molecular Cancer …, 2021 - AACR
BRAFV600E mutation is the most frequent genetic alteration in papillary thyroid cancer
(PTC). β-Catenin (Ctnnb1) is a key downstream component of canonical Wnt signaling …
(PTC). β-Catenin (Ctnnb1) is a key downstream component of canonical Wnt signaling …
[HTML][HTML] Tuft1 promotes thyroid carcinoma cell invasion and proliferation and suppresses apoptosis through the Akt-mTOR/GSK3β signaling pathway
H Liu, J Zhu, Z Mao, G Zhang, X Hu… - American Journal of …, 2018 - ncbi.nlm.nih.gov
In this study, we aimed to investigate the biological functions of Tuftelin 1 (Tuft1) in thyroid
carcinoma (TC) and determine its underlying molecular mechanism. We found that the …
carcinoma (TC) and determine its underlying molecular mechanism. We found that the …
[HTML][HTML] Identification of potential BRAF inhibitor joint therapy targets in PTC based on WGCAN and DCGA
YL Han, XQ Yu, YZ Yin, Z Lv, CY Jia, Y Liao… - Journal of …, 2021 - ncbi.nlm.nih.gov
As the most common mutation in papillary thyroid cancer (PTC), B-type Raf kinase V600E
mutation (BRAF V600E) has become an important target for the clinical treatment of PTC …
mutation (BRAF V600E) has become an important target for the clinical treatment of PTC …
M2‐like tumor‐associated macrophages‐secreted Wnt1 and Wnt3a promotes dedifferentiation and metastasis via activating β‐catenin pathway in thyroid cancer
J Lv, ZP Feng, FK Chen, C Liu, L Jia… - Molecular …, 2021 - Wiley Online Library
Background Thyroid carcinoma (TC) has been a global issue for its rapid increasing
incidence worldwide. Although most TC was not so aggressive with a good prognosis …
incidence worldwide. Although most TC was not so aggressive with a good prognosis …
相关搜索
- autophagy and apoptosis thyroid carcinoma
- autophagy and apoptosis cancer growth
- thyroid carcinoma cancer growth
- thyroid carcinoma prognostic marker
- thyroid cancer dedifferentiation and metastasis
- thyroid carcinoma aberrant expression
- thyroid cancer associated macrophages
- thyroid carcinoma microarray analysis
- thyroid carcinoma candidate genes
- hepatocellular carcinoma cell apoptosis
- thyroid cancer wnt1 and wnt3a
- thyroid carcinoma poor outcomes
- thyroid cancer β catenin