The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity

MF Osuchowski, MS Winkler, T Skirecki… - The Lancet …, 2021 - thelancet.com
The zoonotic SARS-CoV-2 virus that causes COVID-19 continues to spread worldwide, with
devastating consequences. While the medical community has gained insight into the …

Post-acute sequelae of COVID-19: understanding and addressing the burden of multisystem manifestations

M Parotto, M Gyöngyösi, K Howe, SN Myatra… - The Lancet …, 2023 - thelancet.com
Individuals with SARS-CoV-2 infection can develop symptoms that persist well beyond the
acute phase of COVID-19 or emerge after the acute phase, lasting for weeks or months after …

Long COVID: systemic inflammation and obesity as therapeutic targets

LL Florencio… - The Lancet Respiratory …, 2022 - thelancet.com
Management of the post-COVID-19 condition—often referred to as long COVID—is a
challenge for healthcare professionals because of the heterogeneity and complexity of its …

Physiological and biological heterogeneity in COVID-19-associated acute respiratory distress syndrome

LB Ware - The Lancet Respiratory Medicine, 2020 - thelancet.com
One of the most common causes of hospital admission and death in patients with severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is acute respiratory …

Respiratory sequelae of COVID-19: pulmonary and extrapulmonary origins, and approaches to clinical care and rehabilitation

SJ Singh, MM Baldwin, E Daynes, RA Evans… - The Lancet …, 2023 - thelancet.com
Although the exact prevalence of post-COVID-19 condition (also known as long COVID) is
unknown, more than a third of patients with COVID-19 develop symptoms that persist for …

[HTML][HTML] Post-acute COVID-19 syndrome

A Nalbandian, K Sehgal, A Gupta, MV Madhavan… - Nature medicine, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen
responsible for the coronavirus disease 2019 (COVID-19) pandemic, which has resulted in …

Overcoming barriers: the endothelium as a linchpin of coronavirus disease 2019 pathogenesis?

D Gustafson, S Raju, R Wu, C Ching… - … , and vascular biology, 2020 - Am Heart Assoc
Objective: Coronavirus disease 2019 (COVID-19) is a global pandemic involving> 5 500
000 cases worldwide as of May 26, 2020. The culprit is the severe acute respiratory …

[HTML][HTML] The changing demographics of COVID-19

P Venkatesan - The lancet respiratory medicine, 2020 - thelancet.com
As societies around the world begin to reopen after many months of lockdown, a worrying
shift is emerging in the demographic of COVID-19 cases towards individuals aged younger …

Addressing the post-acute sequelae of SARS-CoV-2 infection: a multidisciplinary model of care

AM Parker, E Brigham, B Connolly… - The Lancet …, 2021 - thelancet.com
Summary As of July 31, 2021, SARS-CoV-2 had infected almost 200 million people
worldwide. The growing burden of survivorship is substantial in terms of the complexity of …

[HTML][HTML] Pathophysiology of COVID-19-associated acute respiratory distress syndrome

L Camporota, D Chiumello, M Busana… - The Lancet …, 2021 - thelancet.com
We congratulate Giacomo Grasselli and colleagues for their important and informative work
on the pathophysiology of COVID-19-associated acute respiratory distress syndrome …