Cell death is a critical biological process, serving many important functions within
multicellular organisms. Aberrations in cell death can contribute to the pathology of human …

Mammalian cells adopt several cellular mechanisms to die, including apoptosis, autophagy,
and programmed necrosis. Cell death has an important homeostatic role, mediating the …

Over the past few years, the field of regulated cell death continues to expand and novel
mechanisms that orchestrate multiple regulated cell death pathways are being unveiled …

Simple Summary Inflammation and free radicals can stimulate cell self-destruction.
Inflammation and cell death are vital aspects of most diseases. Accumulation of cell damage …

Cell death is essential for a plethora of physiological processes, and its deregulation
characterizes numerous human diseases. Thus, the in-depth investigation of cell death and …

Pyroptosis, apoptosis, necroptosis, and ferroptosis, which are the most well-studied
regulated cell death (RCD) pathways, contribute to the clearance of infected or potentially …

Naturally occurring cell death or apoptosis is essential for the maintenance of tissue
homeostasis and serves to remove extraneous or dangerous cells in a swift and unobtrusive …

Death is the irreversible cessation of all biological functions that sustain a living organism,
an inevitable end for all living things 1. No human organ is unimportant, but the three most …

Cell death, or conversely cell survival, is a major biological phenomenon. Just as with cell
proliferation and cell differentiation, cell death is a choice that a cell has to make, sometimes …

The aim of Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms is to
present recent developments in cell survival and apoptotic pathways and their involvement …