Purpose Small-scale clinical trials have provided evidence suggesting the effectiveness of
stem-cell therapy (SCT) for patients diagnosed with Crohn's disease (CD). The objective of …

Background and aims Stem cell therapy (SCT) for the treatment of Crohn's disease (CD) is
still in its infancy, and whether SCT is associated with improved outcomes is unclear. We …

Abstract Background Refractory Crohn's disease, especially when complicated by complex
perianal fistula, seriously reduces the patients' quality of life. Preclinical and clinical studies …

Background We explored whether stem cell therapy was effective for animal models and
patients with Crohn's disease (CD). Methods We searched five online databases. The …

Background: Autologous hematopoietic stem cell transplantation (HSCT) has been
proposed for patients with refractory Crohn's disease (CD), but it is associated with mortality …

Background: Crohn's disease (CD) is an autoimmune disease of the gastrointestinal tract,
characterized by relapsing and remitting courses. The disease is debilitating in nature with …

Background: Crohn's disease (CD) therapy is rapidly evolving. Recent and ongoing clinical
trials using immunologically active stem cells (SC) for the treatment of CD demonstrate the …

Background Fistulas have puzzled us all the time and stem cell therapy for it is still in its
infancy. We conducted a meta-analysis and systematic review to evaluate the efficacy of …

Background and aim Crohn's disease (CD) is an inflammatory bowel disease that can affect
any part of the intestine. There is currently no recognized cure for CD because its cause is …

Autologous hematopoietic stem cell transplantation (HSCT) and mesenchymal stromal cell
therapy have been proposed for patients with refractory Crohn's disease (CD) and fistulizing …