Selective estrogen receptor modulators (SERMs) are a diverse group of nonsteroidal
compounds that function as agonists or antagonists for estrogen receptors (ERs) in a target …

Selective estrogen receptor modulators (SERMs) are compounds that exhibit tissue-specific
estrogen receptor (ER) agonist or antagonist activity, and are used for various indications …

The selective estrogen-receptor modulators, or SERMs, chemically diverse nonsteroid
compounds, have tertiary structures that permit binding to the estrogen receptor. These …

Selective estrogen receptor modulators (SERMs) are structurally different compounds that
interact with intracellular estrogen receptors in target organs as estrogen receptor agonists …

Despite the beneficial effects of estrogens in women's health, there is a plethora of evidence
that suggest an important role for these hormones, particularly 17β-estradiol (E2), in the …

Estrogen-containing medicines have been used successfully for the past 50 years for the
treatment of conditions associated with menopause. Although initially considered a …

Selective estrogen receptor modulators (SERMs) are synthetic non-steroidal agents which
have varying estrogen agonist and antagonist activities in different tissues, most likely due to …

In females, estrogens play a key role in reproduction and have beneficial effects on the
skeletal, cardiovascular, and central nervous systems. Most estrogenic responses are …

The sex hormone estrogen is important for many physiologic processes. Prolonged
stimulation of breast ductal epithelium by estrogen, however, can contribute to the …

Synthetic estrogen receptor ligands such as tamoxifen and raloxifene produce biologic
responses which can be either estrogenic or anti-estrogenic, depending upon the tissue in …