[HTML][HTML] Current research approaches to target biofilm infections

E van Tilburg Bernardes, S Lewenza… - Postdoc journal: a …, 2015 - ncbi.nlm.nih.gov
This review will focus on strategies to develop new treatments that target the biofilm mode of
growth and that can be used to treat biofilm infections. These approaches aim to reduce or …

Recent strategies to combat biofilms using antimicrobial agents and therapeutic approaches

L Shrestha, HM Fan, HR Tao, JD Huang - Pathogens, 2022 - mdpi.com
Biofilms are intricate bacterial assemblages that attach to diverse surfaces using an
extracellular polymeric substance that protects them from the host immune system and …

Combination therapies for biofilm inhibition and eradication: a comparative review of laboratory and preclinical studies

S Hawas, AD Verderosa, M Totsika - Frontiers in cellular and infection …, 2022 - frontiersin.org
Microbial biofilms are becoming increasingly difficult to treat in the medical setting due to
their intrinsic resistance to antibiotics. To combat this, several biofilm dispersal agents are …

New frontiers for anti-biofilm drug development

SM Ribeiro, MR Felício, EV Boas, S Gonçalves… - Pharmacology & …, 2016 - Elsevier
Pathogenic microbial biofilm, a consortium of microbial cells protected by a self-produced
polymer matrix, is considered a worldwide challenge due to the inherent antibiotic …

[PDF][PDF] Bacterial biofilm eradication and combating strategies

A Madhusoodhanan, M Minsa… - Asia Pac J Mol Biol …, 2022 - researchgate.net
Biofilm is an aggregation of microorganisms adhered to the substrate and confined in an
extracellular polymeric substance (EPS). The property of enhanced resistance to host …

Strategies for combating bacterial biofilms: A focus on anti-biofilm agents and their mechanisms of action

R Roy, M Tiwari, G Donelli, V Tiwari - Virulence, 2018 - Taylor & Francis
Biofilm refers to the complex, sessile communities of microbes found either attached to a
surface or buried firmly in an extracellular matrix as aggregates. The biofilm matrix …

The principles, mechanisms, and benefits of unconventional agents in the treatment of biofilm infection

J Talapko, I Škrlec - Pharmaceuticals, 2020 - mdpi.com
Today, researchers are looking at new ways to treat severe infections caused by resistance
to standard antibiotic therapy. This is quite challenging due to the complex and …

An overview of biofilm formation–combating strategies and mechanisms of action of antibiofilm agents

ST Asma, K Imre, A Morar, V Herman, U Acaroz… - Life, 2022 - mdpi.com
Biofilm formation on surfaces via microbial colonization causes infections and has become a
major health issue globally. The biofilm lifestyle provides resistance to environmental …

Combating biofilms

L Yang, Y Liu, H Wu, Z Song, N Høiby… - FEMS Immunology & …, 2012 - academic.oup.com
Biofilms are complex microbial communities consisting of microcolonies embedded in a
matrix of self-produced polymer substances. Biofilm cells show much greater resistance to …

Agents that inhibit bacterial biofilm formation

N Rabin, Y Zheng, C Opoku-Temeng, Y Du… - Future medicinal …, 2015 - Taylor & Francis
In the biofilm form, bacteria are more resistant to various antimicrobial treatments. Bacteria in
a biofilm can also survive harsh conditions and withstand the host's immune system …