In a breast tumor xenograft model, the MCT-1 oncogene increases the in vivo tumorgenicity
of MCF7 cells by promoting angiogenesis and inhibiting apoptosis. Increases in the tumor …

Cancer‐related gene expression programs are strongly influenced by posttranscriptional
mechanisms. The RNA‐binding protein HuR is highly abundant in many cancers. Numerous …

HuR, a protein that binds to target mRNAs and can enhance their stability and translation, is
increasingly recognized as a pivotal regulator of gene expression during cell division and …

The RNA-binding proteins involved in regulation of mRNA post-transcriptional processing
and translation control the fates of thousands of mRNA transcripts and basic cellular …

The RNA-binding protein HuR regulates the stability and translation of target mRNAs. While
no HuR mutations have been found in cancer, a link between HuR and malignant …

Human conventional renal cell carcinoma (CRCC) remains resistant to therapy. The RNA-
binding protein HuR regulates the stability and/or translation of multiple messenger RNAs …

Immunohistochemical analysis of paired tumor and normal tissue specimens revealed that
the expression and cytoplasmic abundance of the RNA-binding protein HuR increased with …

Regulation of mRNA decay is an important mechanism controlling gene expression. Steady
state levels of mRNAs can be markedly altered by changes in the decay rate. The control of …

The RNA-binding protein human antigen R (HuR) is a well-established regulator of gene
expression at the posttranscriptional level. Its dysregulation has been implicated in various …

HuR is a ubiquitous nucleocytoplasmic RNA-binding protein that exerts pleiotropic effects on
cell growth and tumorigenesis. In this study, we explored the impact of conditional, tissue …