The water permeability of biological membranes has been a longstanding problem in
physiology, but the proteins responsible for this remained unknown until discovery of the …

Aquaporins (AQP) are integral membrane proteins that serve as channels in the transfer of
water, and in some cases, small solutes across the membrane. They are conserved in …

Although water is the major component of all biological fluids, the molecular pathways for
water transport across cell membranes eluded identification until the discovery of the …

How water permeates cellular membranes and what this means for cell functioning and
several diseases are now emerging from the study of the aquaporins (AQPs), the water …

Abstract Water channels, aquaporins (AQPs), are a family of small integral plasma
membrane proteins that primarily transport water across the plasma membrane. There are …

▪ Abstract The high water permeability characteristic of mammalian red cell membranes is
now known to be caused by the protein AQP1. This channel freely permits movement of …

The molecular basis of membrane water-permeability remained elusive until the recent
discovery of the aquaporin water-channel proteins. The fundamental importance of these …

The aquaporins (AQPs) are a family of small membrane-spanning proteins (monomer size∼
30 kDa) that are expressed at plasma membranes in many cells types involved in fluid …

The study of water transport began long before the molecular identification of water
channels with studies of water-permeable tissues. The discovery of the first aquaporin …

Aquaporin (AQP) 6 belongs to the aquaporin water channel family. Unlike other aquaporins,
AQP6 functions not as a water channel but as an anion-selective channel. Single-channel …