Ghrelin: central and peripheral implications in anorexia nervosa

M Méquinion, F Langlet, S Zgheib, S Dickson… - Frontiers in …, 2013 - frontiersin.org
Increasing clinical and therapeutic interest in the neurobiology of eating disorders reflects
their dramatic impact on health. Chronic food restriction resulting in severe weight loss is a …

Review of novel aspects of the regulation of ghrelin secretion

O Al Massadi, PV Lear, TD Muller… - Current drug …, 2014 - ingentaconnect.com
The role of ghrelin in regulating metabolism and energy balance has been a subject of
intense focus ever since its discovery. Ghrelin regulates energy balance in the short term by …

The role of ghrelin in weight-regulation disorders: implications in clinical practice

S Solomou, M Korbonits - Hormones, 2014 - Springer
Ghrelin, an orexigenic protein with a unique lipid chain modification, is considered to be an
important gut-brain signal for appetite control and energy balance. The ghrelin receptor …

The role of ghrelin in metabolic regulation

J Pinkney - Current Opinion in Clinical Nutrition & Metabolic Care, 2014 - journals.lww.com
Ghrelin functions primarily as a short-term metabolic switch at the onset of fasting, gearing
the fuel economy away from glucose uptake, conserving glucose for vital functions …

Ghrelin and the central regulation of feeding and energy balance

A Abizaid, TL Horvath - Indian journal of endocrinology and …, 2012 - journals.lww.com
Ghrelin was discovered in 1999 as growth hormone secretagouge released from the gut.
Soon after it was recognized that ghrelin is a fundamental driver of appetite in rodents and …

Weight gain decreases elevated plasma ghrelin concentrations of patients with anorexia nervosa

B Otto, U Cuntz, E Fruehauf, R Wawarta… - European journal of …, 2001 - academic.oup.com
Objective Ghrelin is a new gastric hormone that has been identified as an endogenous
ligand for the growth hormone (GH) secretagogue receptor subtype 1a (GHS-R1a). Ghrelin …

Minireview: ghrelin and the regulation of energy balance—a hypothalamic perspective

TL Horvath, S Diano, P Sotonyi, M Heiman… - …, 2001 - academic.oup.com
The recently discovered hormone, ghrelin, has been recognized as an important regulator of
GH secretion and energy homeostasis. Orexigenic and adipogenic ghrelin is produced by …

[PDF][PDF] The role of ghrelin in the regulation of food intake in patients with obesity and anorexia nervosa.

I Dostálová, M Haluzík - Physiological research, 2009 - biomed.cas.cz
Gastrointestinal hormones play an important role in the neuroendocrine regulation of food
intake and postprandial satiety. Ghrelin is a 28-amino acid orexigenic peptide produced …

Ghrelin: a link between eating disorders, obesity and reproduction

C Gottero, F Broglio, F Prodam, S Destefanis… - Nutritional …, 2004 - Taylor & Francis
Ghrelin, a 28-amino acid acylated peptide predominantly produced by the stomach, displays
strong GH-releasing activity mediated by the hypothalamic-pituitary GH secretagogues …

The endocrine response to acute ghrelin administration is blunted in patients with anorexia nervosa, a ghrelin hypersecretory state

F Broglio, L Gianotti, S Destefanis… - Clinical …, 2004 - Wiley Online Library
Summary objective Ghrelin, a gastric‐derived natural ligand of the GH secretagogue (GHS)‐
receptor (GHS‐R), strongly stimulates GH secretion but also possesses other …