From LncRNA to metastasis: The MALAT1-EMT axis in cancer progression

R Thapa, O Afzal, M Afzal, G Gupta, AA Bhat… - … -Research and Practice, 2023 - Elsevier
Cancer is a complex disease that causes abnormal genetic changes and unchecked cellular
growth. It also causes a disruption in the normal regulatory processes that leads to the …

MALAT1: A key regulator in lung cancer pathogenesis and therapeutic targeting

AA Bhat, O Afzal, M Afzal, G Gupta, R Thapa… - … -Research and Practice, 2023 - Elsevier
Lung cancer remains a formidable global health burden, necessitating a comprehensive
understanding of the underlying molecular mechanisms driving its progression. Recently …

MALAT1: a potential biomarker in cancer

ZX Li, QN Zhu, HB Zhang, Y Hu, G Wang… - Cancer management …, 2018 - Taylor & Francis
Purpose The research of long non-coding RNAs (lncRNAs) has become a new passion with
the discovery of abundant new lncRNAs and extensive investigation of their roles in various …

[PDF][PDF] MALAT1-mediated tumorigenesis

J Liu, WX Peng, YY Mo, D Luo - Front Biosci (Landmark Ed), 2017 - article.imrpress.com
Functional genomics studies over the past decades have unveiled that the human genome
transcribes a large amount of long noncoding RNAs (lncRNAs) which have been implicated …

[HTML][HTML] MALAT1 is an oncogenic long non-coding RNA associated with tumor invasion in non-small cell lung cancer regulated by DNA methylation

F Guo, L Guo, Y Li, Q Zhou, Z Li - International journal of clinical …, 2015 - ncbi.nlm.nih.gov
MALAT1 is an important long noncoding RNA in tumor progression. Here we showed that
the expression of MALAT1 was upregulated in non-small cell lung cancer cells (NSCLCs) or …

[HTML][HTML] Functional and prognostic significance of long non-coding RNA MALAT1 as a metastasis driver in ER negative lymph node negative breast cancer

M Jadaliha, X Zong, P Malakar, T Ray, DK Singh… - Oncotarget, 2016 - ncbi.nlm.nih.gov
MALAT1 (metastasis associated lung adenocarcinoma transcript1) is a conserved long non-
coding RNA, known to regulate gene expression by modulating transcription and post …

Regulatory networks of LncRNA MALAT-1 in cancer

S Fu, Y Wang, H Li, L Chen, Q Liu - Cancer management and …, 2020 - Taylor & Francis
Long noncoding (lnc) RNAs are a group of RNAs with a length greater than 200 nt that do
not encode a protein but play an essential role in regulating the expression of target genes …

New Insights into Long Non-Coding RNA MALAT1 in Cancer and Metastasis

Y Sun, L Ma - Cancers, 2019 - mdpi.com
Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is one of the most
abundant, long non-coding RNAs (lncRNAs) in normal tissues. This lncRNA is highly …

LncRNA MALAT1 promotes migration and invasion of non-small-cell lung cancer by targeting miR-206 and activating Akt/mTOR signaling

Y Tang, GM Xiao, YJ Chen, Y Deng - Anti-Cancer Drugs, 2018 - journals.lww.com
Long noncoding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript 1
(MALAT1) functions as a crucial regulator of metastasis in lung cancer. The aim of this study …

LncRNA MALAT1 accelerates non‐small cell lung cancer progression via regulating miR‐185‐5p/MDM4 axis

D Wang, S Zhang, M Zhao, F Chen - Cancer medicine, 2020 - Wiley Online Library
Non‐small cell lung cancer (NSCLC) is the commonest malignancy with high death rate
around the world. LncRNA metastasis‐associated lung adenocarcinoma transcript 1 …